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Single Nucleotide Polymorphism Africa Pre-Eclampsia Genetic Variations Vascular Endothelial Growth Factor Uganda Sanger Sequencing Genetic Biomarkers Humans Pre-Eclampsia Genetic Predisposition To Disease Vascular Endothelial Growth Factor A Case-Control Studies Pregnancy Genotype Polymorphism Single Nucleotide Pregnant Women Female

Methylation Gene Duplication Structural Variation Gwas Snp Calling Humans Arabidopsis Sequence Analysis Dna Polymorphism Single Nucleotide Genome Plant Genome-Wide Association Study Dna Copy Number Variations

Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic...

Humans Cardiovascular Diseases Genetic Predisposition To Disease Proteome Genotype Phenotype Polymorphism Single Nucleotide Genome-Wide Association Study

Gwas Transcriptomics Exfoliation Syndrome Twas Gtex Predicted Expressions Humans Amino Acid Oxidoreductases Dna-Binding Proteins Rna Messenger Gene Expression Mutation Missense Polymorphism Single Nucleotide

Allele Frequency Case Fatality Rate Humans Serine Endopeptidases Mortality Gene Frequency Polymorphism Single Nucleotide Models Molecular Asian Continental Ancestry Group European Continental Ancestry Group Republic Of Korea

Our study describes breast cancer risk loci using a cross-ancestry GWAS approach. We first identify variants that are associated with breast cancer at P < 0.05 from African ancestry GWAS meta-analysis (9241 cases and 10193...

Humans Breast Neoplasms Genetic Predisposition To Disease Polymorphism Single Nucleotide Quantitative Trait Loci Introns African Continental Ancestry Group European Continental Ancestry Group Female Genome-Wide Association Study

The mechanism behind transgenerational epigenetic inheritance is unclear, particularly through the maternal grandparental line. We previously showed that disruption of folate metabolism in mice by the Mtrr hypomorphic mutation...

Liver Germ Cells Spermatozoa Trophoblasts Animals Mice Mice Folic Acid Ferredoxin-Nadp Reductase Cell Cycle Proteins Transcription Factors Pedigree Dna Methylation Epigenesis Genetic Heredity Inheritance Patterns Phenotype Polymorphism Single Nucleotide Female Male Embryo Mammalian Histone Chaperones Epigenomics Biomarkers Maternal Inheritance Whole Genome Sequencing

Shigella sonnei is the most common agent of shigellosis in high-income countries, and causes a significant disease burden in low- and middle-income countries. Antimicrobial resistance is increasingly common in all settings....

Humans Shigella Sonnei Dysentery Bacillary Azithromycin Ciprofloxacin Anti-Bacterial Agents Microbial Sensitivity Tests Genetics Population Genomics Phylogeny Drug Resistance Multiple Bacterial Genotype Polymorphism Single Nucleotide Genome Bacterial Geography United States Australia England Global Health Whole Genome Sequencing