Search: AGOSR

Results: 6

No Association of a Vascular Endothelial Growth Factor a (Vegfa) Gene Polymorphism with Pre-Eclampsia Among Pregnant Women in Uganda.

Sheila,Nabweyambo; Stephen,Kanyerezi; John H-O,Petterson; Fred Ashaba,Katabazi; Alfred,Ssekagiri; Savannah,Mwesigwa; Gerald,Mboowa; Faith,Nakazzi; Annette,Keesiga; Moses,Adroma; Freddie,Bwanga; Naomi,McGovern; Obondo James,Sande; Annettee,Nakimuli

Single Nucleotide Polymorphism Africa Pre-Eclampsia Genetic Variations Vascular Endothelial Growth Factor Uganda Sanger Sequencing Genetic Biomarkers Humans Pre-Eclampsia Genetic Predisposition To Disease Vascular Endothelial Growth Factor A Case-Control Studies Pregnancy Genotype Polymorphism Single Nucleotide Pregnant Women Female

Published by: BMC genomics

Published on: Apr 17, 2023

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Molecular Genetic Characteristics of Fanci, a Proposed New Ovarian Cancer Predisposing Gene.

Caitlin T,Fierheller; Wejdan M,Alenezi; Corinne,Serruya; Timothée,Revil; Setor,Amuzu; Karine,Bedard; Deepak N,Subramanian; Eleanor,Fewings; Jeffrey P,Bruce; Stephenie,Prokopec; Luigi,Bouchard; Diane,Provencher; William D,Foulkes; Zaki,El Haffaf; Anne-Marie,Mes-Masson

Ovarian Cancer Hereditary Cancer Whole Exome Sequencing Tcga Fanci Fanconi Anemia Pathway Cancer Predisposing Gene Humans Ovarian Neoplasms Genetic Predisposition To Disease Molecular Biology Mutation Genes Female Fanconi Anemia Complementation Group Proteins

Published by: Genes

Published on: Mar 28, 2023

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The Impact of Coding Germline Variants on Contralateral Breast Cancer Risk and Survival.

Anna,Morra; Nasim,Mavaddat; Taru A,Muranen; Thomas U,Ahearn; Jamie,Allen; Irene L,Andrulis; Päivi,Auvinen; Heiko,Becher; Sabine,Behrens; Carl,Blomqvist; Stig E,Bojesen; Manjeet K,Bolla; Hiltrud,Brauch; Nicola J,Camp; Sara,Carvalho

Evidence linking coding germline variants in breast cancer (BC)-susceptibility genes other than BRCA1, BRCA2, and CHEK2 with contralateral breast cancer (CBC) risk and breast cancer-specific survival (BCSS) is scarce. The aim of...

Survival Breast Cancer Susceptibility Genes Contralateral Breast Cancer Risk Coding Germline Variants Germ Cells Humans Breast Neoplasms Genetic Predisposition To Disease Germ-Line Mutation Genes Female

Published by: American journal of human genetics

Published on: Mar 28, 2023

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Genome-Wide Genotype-Serum Proteome Mapping Provides Insights Into the Cross-Ancestry Differences in Cardiometabolic Disease Susceptibility.

Fengzhe,Xu; Evan Yi-Wen,Yu; Xue,Cai; Liang,Yue; Li-Peng,Jing; Xinxiu,Liang; Yuanqing,Fu; Zelei,Miao; Min,Yang; Menglei,Shuai; Wanglong,Gou; Congmei,Xiao; Zhangzhi,Xue; Yuting,Xie; Sainan,Li

Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic...

Humans Cardiovascular Diseases Genetic Predisposition To Disease Proteome Genotype Phenotype Polymorphism Single Nucleotide Genome-Wide Association Study

Published by: Nature Communications

Published on: Mar 19, 2023

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Finngen Provides Genetic Insights from a Well-Phenotyped Isolated Population.

Mitja I,Kurki; Juha,Karjalainen; Priit,Palta; Timo P,Sipilä; Kati,Kristiansson; Kati M,Donner; Mary P,Reeve; Hannele,Laivuori; Mervi,Aavikko; Mari A,Kaunisto; Anu,Loukola; Elisa,Lahtela; Hannele,Mattsson; Päivi,Laiho; Pietro,Della Briotta Parolo

Humans Disease Genetic Predisposition To Disease Gene Frequency Phenotype Middle Aged Estonia Finland Meta-Analysis As Topic Genome-Wide Association Study United Kingdom White People

Published by: Nature

Published on: Feb 19, 2023

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Cross-Ancestry Gwas Meta-Analysis Identifies Six Breast Cancer Loci in African and European Ancestry Women.

Babatunde,Adedokun; Zhaohui,Du; Guimin,Gao; Thomas U,Ahearn; Kathryn L,Lunetta; Gary,Zirpoli; Jonine,Figueroa; Esther M,John; Leslie,Bernstein; Wei,Zheng; Jennifer J,Hu; Regina G,Ziegler; Sarah,Nyante; Elisa V,Bandera; Sue A,Ingles

Our study describes breast cancer risk loci using a cross-ancestry GWAS approach. We first identify variants that are associated with breast cancer at P < 0.05 from African ancestry GWAS meta-analysis (9241 cases and 10193...

Humans Breast Neoplasms Genetic Predisposition To Disease Polymorphism Single Nucleotide Quantitative Trait Loci Introns African Continental Ancestry Group European Continental Ancestry Group Female Genome-Wide Association Study

Published by: Nature Communications

Published on: Aug 11, 2021