Plasma membrane mimetics can potentially play a vital role in drug discovery and immunotherapy owing to the versatility to assemble facilely cellular membranes on surfaces and/or nanoparticles, allowing for direct assessment of...
Novel therapeutic and diagnostic methods are sorely needed for gliomas, which contribute yearly to hundreds of thousands of cancer deaths worldwide. Despite the outpouring of research efforts and funding aimed at improving...
Hydroxyapatite [Ca10(PO4)6(OH)2] (HAp) is a calcium phosphate mineral of great interest in biomaterials development because it is the main component of the mineral phase of bones and teeth’s of animals and humans. HAp plays a...
This review proposes to present how materials at nanolevel scale can contribute to the development of three-dimensional (3D) structures, human tissues, and organs which have macrolevel organization. Specific nanomaterials such...
Liposomes were synthesized using the thin film method. A lyophilized power of egg-derived phosphatidylcholine, stearylamine, and cholesterol were added to ethanol and dried under argon to form a lipid cake. The lipid cake was...
Purple membrane (PM, ?" role="presentation">?max" role="presentation">max 570 nm) of H. halobium on treatment with sulphuric acid changes its colour to blue (?" role="presentation">?max" role="presentation">max 608 nm). The...
The hybridization of DNA by sequential electrostatic and hydrogen-bonding immobilization of single-stranded complementary oligonucleotides at the air-water interface with cationic Langmuir monolayers is demonstrated. The...
Terahertz reflectometry and spectrometry was used to investigate the permeation kinetics and concentration profile of active ingredients in to the stratum corneum. To our knowledge this is the first effort of direct...
The formation of composite films of double-stranded DNA and cationic lipid molecules (octadecylamine, ODA) and the hybridization of complementary single-stranded DNA molecules in such composite films are demonstrated. The...
Use of a Steglich esterification to covalently attach erythromycin onto a single-walled carbon nanotube to circumvent the efflux pump mechanism of resistance in Enterococcus.
Hybridization of complementary oligonucleotides mediated by a cationic surfactant at the water/hexane interface leads to hydrophobic, double-helical DNA which may be readily phase transferred to the organic phase and cast into...
The structure of the type I tetraheme cytochrome c3 from Desulfovibrio desulfuricans G20 was determined to 1.5 A? by X-ray crystallography. In addition to the oxidized form, the structure of the molybdate-bound form of the...
The delivery of nanoparticles--microscopic cargo that can play an important role in healthcare--is a straightforward concept with a highly complex execution. Many common drugs are hydrophobic and unable to travel through the...