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Results: 101
Obsessive-compulsive disorder in adults with high-functioning autism spectrum disorder
Background: Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring...
The Owl, the Fox, and the Mole
Declan Seviour
Jul 05, 2022
n/a
Published by: Memorial University of Newfoundland
The Owl, the Fox, and the Mole
Declan Seviour
Jul 05, 2022
n/a
Published by: Memorial University of Newfoundland
Obsessive-compulsive disorder in adults with high-functioning autism spectrum disorder
Background: Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring...
Evaluating the provision of paediatric liaison psychiatry services in England.
Declan Hines, Tamsin Ford, Sophie Westwood, Jessica R Barrett, Birgit Westphal, Virginia Davies, William Lee
Mar 03, 2023
BACKGROUND: Liaison psychiatry provision for children and young people in England is poorly evaluated. AIMS: We sought to evaluate paediatric liaison psychiatry provision and develop recommendations to improve practice. METHOD...
Cognitive behavior therapy for comorbid Obsessive-Compulsive Disorder in high functioning Autism Spectrum Disorders
Ailsa J Russell, Amita Jassi, Miquel A Fullana, Hilary Mack, Kate Johnston, Isobel Heyman, Declan G Murphy, David Mataix-Cols
Aug 01, 2013
Background: High rates of anxiety disorders, particularly Obsessive Compulsive Disorder (OCD) are reported in people with Autism Spectrum Disorders (ASD). Group cognitive behavioural (CBT) treatment has been found effective for...
EU-AIMS Longitudinal European Autism Project (LEAP)
Johan Isaksson, Kristiina Tammimies, Janina Neufeld, Élodie Cauvet, Karl Lundin, Jan K Buitelaar, Eva Loth, Declan GM Murphy, Will Spooren, Sven Bölte, EU-AIMS LEAP group
May 09, 2019
EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) has...
White and gray matter damage in primary progressive MS
Benedetta Bodini, Declan Chard, Daniel R Altmann, Daniel Tozer, David H Miller, Alan J Thompson, Claudia Wheeler-Kingshott, Olga Ciccarelli
Jun 22, 2018
OBJECTIVE: The temporal relationship between white matter (WM) and gray matter (GM) damage in vivo in early primary progressive multiple sclerosis (PPMS) was investigated testing 2 hypotheses: (1) WM tract abnormalities predict...
Large variation in conservative management of low-risk prostate cancer in Australia and New Zealand.
How do core autism traits and associated symptoms relate to quality of life? Findings from the Longitudinal European Autism Project.
Bethany Fm Oakley, Julian Tillmann, Jumana Ahmad, Daisy Crawley, Antonia San José Cáceres, Rosemary Holt, Tony Charman, Tobias Banaschewski, Jan Buitelaar, Emily Simonoff, Declan Murphy, Eva Loth
Apr 10, 2021
Previous studies suggest that some autistic individuals report lower satisfaction, or well-being, with different aspects of everyday life than those without autism. It is unclear whether this might be partly explained by...
ADvanced IMage Algebra (ADIMA)
Marios C Yiannakas, Daniel J Tozer, Klaus Schmierer, Declan T Chard, Valerie M Anderson, Daniel R Altmann, David H Miller, Claudia AM Wheeler-Kingshott
Sep 01, 2021
BACKGROUND: There are modest correlations between multiple sclerosis (MS) disability and white matter lesion (WML) volumes, as measured by T2-weighted (T2w) magnetic resonance imaging (MRI) scans (T2-WML). This may partly...
ADIMA MRI methods brain lesion sub-classification lesion volume Magnetic Resonance Imaging relapsing–remitting multiple sclerosis white matter lesions Algorithms Female Humans Image Processing Computer-Assisted Magnetic Resonance Imaging Male Middle Aged Multiple Sclerosis Relapsing-Remitting Observer Variation Predictive Value of Tests Reproducibility of Results white matter
Shared and Disorder-Specific Neurocomputational Mechanisms of Decision-Making in Autism Spectrum Disorder and Obsessive-Compulsive Disorder.
Christina O Carlisi, Luke Norman, Clodagh M Murphy, Anastasia Christakou, Kaylita Chantiluke, Vincent Giampietro, Andrew Simmons, Michael Brammer, Declan G Murphy, David Mataix-Cols, Katya Rubia, MRC AIMS Consortium
May 14, 2019
Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) often share phenotypes of repetitive behaviors, possibly underpinned by abnormal decision-making. To compare neural correlates underlying decision-making...
Autism spectrum disorder computational modeling decision-making fMRI Obsessive-Compulsive Disorder Adolescent Autism spectrum disorder Brain Brain Mapping Child Computer Simulation Decision Making Feedback Psychological Formative Feedback Gambling Humans Magnetic Resonance Imaging Male Models Neurological Neural Pathways Neuropsychological Tests Obsessive-Compulsive Disorder Reinforcement psychology
Familial risk of autism alters subcortical and cerebellar brain anatomy in infants and predicts the emergence of repetitive behaviors in early childhood.
Inês Pote, Siying Wang, Vaheshta Sethna, Anna Blasi, Eileen Daly, Maria Kuklisova-Murgasova, Sarah Lloyd-Fox, Evelyne Mercure, Paula Busuulwa, Vladimira Stoencheva, Tony Charman, Steven Cr Williams, Mark H Johnson, Declan GM Murphy, Grainne M McAlonan, BASIS Team
May 09, 2019
Autism spectrum disorder (ASD) is a common neurodevelopmental condition, and infant siblings of children with ASD are at a higher risk of developing autistic traits or an ASD diagnosis, when compared to those with typically...
Autism spectrum disorder cerebellum familial risk infants magnetic resonance imaging-structural mother-infant interaction subcortex Autism spectrum disorder Brain Female Genetic Predisposition to Disease Humans Infant Magnetic Resonance Imaging Male Organ Size Prospective Studies risk Siblings Stereotyped Behavior
COVID-19 health and social care access for autistic people
Bethany Oakley, Julian Tillmann, Amber Ruigrok, Aurélie Baranger, Christian Takow, Tony Charman, Emily Jones, James Cusack, Mary Doherty, Pierre Violland, Agnieszka Wroczyńska, Emily Simonoff, Jan K Buitelaar, Louise Gallagher, Declan GM Murphy, AIMS-2-TRIALS ECRAN & the AIMS-2-TRIALS Consortium
Jun 18, 2021
BACKGROUND: The global COVID-19 pandemic has had an unprecedented impact on European health and social care systems, with demands on testing, hospital and intensive care capacity exceeding available resources in many regions....
Examining volumetric gradients based on the frustum surface ratio in the brain in autism spectrum disorder.
Caroline Mann, Tim Schäfer, Anke Bletsch, Maria Gudbrandsen, Eileen Daly, John Suckling, Edward T Bullmore, Michael V Lombardo, Meng-Chuan Lai, Michael C Craig, MRC AIMS Consortium, Simon Baron-Cohen, Declan GM Murphy, Christine Ecker
Feb 15, 2021
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that is accompanied by neurodevelopmental differences in regional cortical volume (CV), and a potential layer-specific pathology. Conventional measures of...
Molecular characterization of the conoid complex in Toxoplasma reveals its conservation in all apicomplexans, including Plasmodium species.
Ludek Koreny, Mohammad Zeeshan, Konstantin Barylyuk, Eelco C Tromer, Jolien JE van Hooff, Declan Brady, Huiling Ke, Sara Chelaghma, David JP Ferguson, Laura Eme, Rita Tewari, Ross F Waller
Feb 03, 2021
The apical complex is the instrument of invasion used by apicomplexan parasites, and the conoid is a conspicuous feature of this apparatus found throughout this phylum. The conoid, however, is believed to be heavily reduced or...
Cognitive behavior therapy for comorbid Obsessive-Compulsive Disorder in high functioning Autism Spectrum Disorders
Ailsa J Russell, Amita Jassi, Miquel A Fullana, Hilary Mack, Kate Johnston, Isobel Heyman, Declan G Murphy, David Mataix-Cols
Aug 01, 2013
Background: High rates of anxiety disorders, particularly Obsessive Compulsive Disorder (OCD) are reported in people with Autism Spectrum Disorders (ASD). Group cognitive behavioural (CBT) treatment has been found effective for...
Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription
Mami Oikawa, Angela Simeone, Eva Hormanseder, Marta Teperek, Vincent Gaggioli, Alan O’Doherty, Emma Falk, Matthieu Sporniak, Clive D’Santos, Valar Nila Roamio Franklin, Kamal Kishore, Charles R. Bradshaw, Declan Keane, Thomas Freour, Laurent David, Adrian T. Grzybowski, Alexander J. Ruthenburg, John Gurdon, Jerome Jullien
Jul 28, 2021
Abstract: Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all...
Atypically rightward cerebral asymmetry in male adults with autism stratifies individuals with and without language delay.
Dorothea L Floris, Meng-Chuan Lai, Tibor Auer, Michael V Lombardo, Christine Ecker, Bhismadev Chakrabarti, Sally J Wheelwright, Edward T Bullmore, Declan GM Murphy, Simon Baron-Cohen, John Suckling
Oct 16, 2015
autism cortical asymmetry language delay lateralization volumetric MRI Acoustic Stimulation Adolescent Adult Autistic Disorder Brain Mapping Cerebral Cortex Cognition Disorders Functional Laterality Humans Image Processing Computer-Assisted Language Development Disorders Magnetic Resonance Imaging Male Neuropsychological Tests Photic Stimulation Psychiatric Status Rating Scales Space Perception Statistics as Topic Young Adult
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression.
Mary-Ellen Lynall, Lorinda Turner, Junaid Bhatti, Jonathan Cavanagh, Peter de Boer, Valeria Mondelli, Declan Jones, Wayne C Drevets, Philip Cowen, Neil A Harrison, Carmine M Pariante, Linda Pointon, Menna R Clatworthy, Edward Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium
Dec 11, 2019
In Vivo Evidence of Reduced Integrity of the Gray-White Matter Boundary in Autism Spectrum Disorder.
Derek Sayre Andrews, Thomas A Avino, Maria Gudbrandsen, Eileen Daly, Andre Marquand, Clodagh M Murphy, Meng-Chuan Lai, Michael V Lombardo, Amber NV Ruigrok, Steven C Williams, Edward T Bullmore, The Mrc Aims Consortium, John Suckling, Simon Baron-Cohen, Michael C Craig, Declan GM Murphy, Christine Ecker
Aug 17, 2017
Atypical cortical organization and reduced integrity of the gray-white matter boundary have been reported by postmortem studies in individuals with autism spectrum disorder (ASD). However, there are no in vivo studies that...
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