Search
Results: 1790
Profiling IT Security and Interoperability in Brazilian Health Organisations From a Business Perspective
Rui Rijo, Ricardo Martinho, Adicinéia Oliveira, Domingos Alves, Zilma Reis, Cátia Santos-Pereira, Manuel Correia, Luís Antunes, Ricardo Cruz-Correia
Apr 01, 2020
The proliferation of electronic health (e-Health) initiatives in Brazil over the last 2 decades has resulted in a considerable fragmentation within health information technology (IT), with a strong political interference. The...
Published by: IGI Global Scientific Publishing
IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.
Widespread seasonal gene expression reveals annual differences in human immunity and physiology.
SAX-Quantile Based Multiresolution Approach for Finding Heatwave Events in Summer Temperature Time Series
Time series pattern discovery is of great importance in a large variety of environmental and engineering applications, from supporting predictive models to helping to understand hidden underlying processes. This work develops a...
In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment
RC Ferreira, DB Rainbow, A Rubio García, ML Pekalski, L Porter, JJ Oliveira, F Waldron-Lynch, LS Wicker, JA Todd
Jul 04, 2017
We provide in this paper a detailed characterization of the human peripheral CD4$^+$ CD127$^{low}$CD25$^+$ regulatory T cell (Treg) compartment, with a particular emphasis in defining the population expressing higher levels of...
Modelling and Coordination of Building design
Marcio Presente de Souza, Beatriz Campos Fialho, Rita Cristina Ferreira, Marcio Minto Fabricio, Ricardo Codinhoto
Jan 31, 2023
The implementation of Building Information Modelling (BIM) in the Architecture, Engineering, Construction and Operations (AECO) industry requires multidisciplinary teams equipped with new technical and managerial skills....
Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression.
Ricardo C Ferreira, Xaquin Castro Dopico, João J Oliveira, Daniel B Rainbow, Jennie H Yang, Dominik Trzupek, Sarah A Todd, Mhairi McNeill, Maristella Steri, Valeria Orrù, Edoardo Fiorillo, Daniel JM Crouch, Marcin L Pekalski, Francesco Cucca, Tim I Tree, Tim J Vyse, Linda S Wicker, John A Todd
Jan 03, 2020
In systemic lupus erythematosus (SLE), perturbed immunoregulation underpins a pathogenic imbalance between regulatory and effector CD4+ T-cell activity. However, to date, the characterization of the CD4+ regulatory T cell (Treg)...
FOXP3 PD-1 PTPN22 Arg620Trp Autoimmunity Immunotherapy regulatory T cells (tregs) systemic lupus erythematosus (SLE) type I interferon Adult Aged Aged 80 and over Alleles Autoimmunity Female Forkhead Transcription Factors Humans Interleukin-2 Lupus Erythematosus Systemic Male Middle Aged Programmed Cell Death 1 Receptor Protein Tyrosine Phosphatase Non-Receptor Type 22 risk T-Lymphocytes Regulatory Young Adult
SAX-Quantile Based Multiresolution Approach for Finding Heatwave Events in Summer Temperature Time Series
Time series pattern discovery is of great importance in a large variety of environmental and engineering applications, from supporting predictive models to helping to understand hidden underlying processes. This work develops a...
Creating Extreme Weather Time Series through a Quantile Regression Ensemble
Heat waves give rise to order of magnitude higher mortality rates than other weather-related natural disasters. Unfortunately both the severity and amplitude of heat waves are predicted to increase worldwide as a consequence...
Modelling and Coordination of Building design
Marcio Presente de Souza, Beatriz Campos Fialho, Rita Cristina Ferreira, Marcio Minto Fabricio, Ricardo Codinhoto
Jan 31, 2023
The implementation of Building Information Modelling (BIM) in the Architecture, Engineering, Construction and Operations (AECO) industry requires multidisciplinary teams equipped with new technical and managerial skills....
Creating Extreme Weather Time Series through a Quantile Regression Ensemble
Heat waves give rise to order of magnitude higher mortality rates than other weather-related natural disasters. Unfortunately both the severity and amplitude of heat waves are predicted to increase worldwide as a consequence...
Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction
André Ferreira Castro, Lothar Baltruschat, Tomke Stürner, Amirhoushang Bahrami, Peter Jedlicka, Gaia Tavosanis, Hermann Cuntz
Jan 27, 2021
Class I ventral posterior dendritic arborisation (c1vpda) proprioceptive sensory neurons respond to contractions in the Drosophila larval body wall during crawling. Their dendritic branches run along the direction of...
Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction.
André Ferreira Castro, Lothar Baltruschat, Tomke Stürner, Amirhoushang Bahrami, Peter Jedlicka, Gaia Tavosanis, Hermann Cuntz
Feb 08, 2021
Class I ventral posterior dendritic arborisation (c1vpda) proprioceptive sensory neurons respond to contractions in the Drosophila larval body wall during crawling. Their dendritic branches run along the direction of...
D. melanogaster computer model dendrite function dendrite growth dendrite retraction developmental biology Mechanotransduction neuroscience self-organisation Animals Animals Genetically Modified Dendrites Drosophila Drosophila Proteins Gene Expression Regulation Developmental Green Fluorescent Proteins Morphogenesis Sensory Receptor Cells
TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway.
Jun Wang, Ricardo Ferreira, Wanhua Lu, Samatha Farrow, Kate Downes, Lutz Jermutus, Ralph Minter, Rafia S Al-Lamki, Jordan S Pober, John R Bradley
Sep 08, 2018
Human T regulatory cells (T regs) express high levels of TNF receptor 2 (TNFR2). Ligation of TNFR2 with TNF, which can recognise both TNFR1 and TNFR2, or with a TNFR2-selective binding molecule, DARPin 18 (D18) activates...
Cell Nucleus Cell Proliferation Cells Cultured Gene Expression Regulation Healthy Volunteers Humans Interleukin-2 NF-KappaB Inhibitor alpha NF-kappa B p52 Subunit Primary Cell Culture Proteolysis Receptors Tumor Necrosis Factor Type II Recombinant Fusion Proteins Signal Transduction T-Lymphocytes Regulatory Transcription Factor RelB
A Radial Estimation-of-Distribution Algorithm for the Job-Shop Scheduling Problem
Ricardo Pérez-Rodríguez
Jan 01, 2022
The job-shop environment has been widely studied under different approaches. It is due to its practical characteristic that makes its research interesting. Therefore, the job-shop scheduling problem continues being attracted to...
Published by: IGI Global Scientific Publishing
Repeated dribbling ability in young soccer players
J Duarte, Oscar Tavares, J Valente-dos-Santos, V Severino, Alex Amed, Ricardo Rebelo-Goncalves, J Pereira, Vasco Vaz, Susana Povoas, A Seabra, Sean Cumming, Manuel Coelho-e-Silva
Jan 01, 0001
The intermittent nature of match performance in youth soccer supports relevance of ability to repeatedly produce high-intensity actions with short recovery periods. This study was aimed to examine the reproducibility of a...
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Dominik Trzupek, Melanie Dunstan, Antony J. Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B. Rainbow, Dominik Aschenbrenner, Joanne L. Jones, Holm H. Uhlig, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira
Jun 24, 2021
Abstract: Background: Traditionally, the transcriptomic and proteomic characterisation of CD4+ T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing...
What Do Students Think of Mobile Chemistry Games?
The impact of digital games on chemistry education has received less attention compared to other scientific fields. This research gap resulted in a limited understanding of how to effectively design mobile chemistry games (MCG)...
Published by: IGI Global Scientific Publishing
Repeated dribbling ability in young soccer players
J Duarte, Oscar Tavares, J Valente-dos-Santos, V Severino, Alex Amed, Ricardo Rebelo-Goncalves, J Pereira, Vasco Vaz, Susana Povoas, A Seabra, Sean Cumming, Manuel Coelho-e-Silva
Jan 01, 0001
The intermittent nature of match performance in youth soccer supports relevance of ability to repeatedly produce high-intensity actions with short recovery periods. This study was aimed to examine the reproducibility of a...
Human forager response to abrupt climate change at 8.2 ka on the Atlantic coast of Europe.
A Physiological-Monitoring Electronic Platform for Cattle Grazing Systems
Ricardo Santos, Fabiana Alves, Patrik Bressan, Ricardo Aguiar, Wellington Santos, Rafael Costa
Jul 01, 2020
In this work, we present a non-invasive electronic platform for physiological data acquisition on cattle grazing systems. The platform can be used for dairy and beef cattle to continuously monitor physiological variables such as...
Published by: IGI Global Scientific Publishing
Human forager response to abrupt climate change at 8.2 ka on the Atlantic coast of Europe.
Xylose-Based Polyethers and Polyesters Via ADMET Polymerization toward Polyethylene-Like Materials
One of the challenges of developing bioderived polymers is to obtain materials with competitive properties. This study investigates the structure-properties relationships of polyesters and polyethers that can be derived from...
Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes.
WS Thompson, ML Pekalski, HZ Simons, DJ Smyth, X Castro-Dopico, H Guo, C Guy, DB Dunger, S Arif, M Peakman, C Wallace, LS Wicker, JA Todd, RC Ferreira
Feb 21, 2020
The appearance of circulating islet-specific autoantibodies before disease diagnosis is a hallmark of human type 1 diabetes (T1D), and suggests a role for B cells in the pathogenesis of the disease. Alterations in the peripheral...
B lymphocytes il-2 IL-21 PTPN22 human immunology Immunophenotyping type 1 diabetes Adolescent Adult Age Factors Autoantibodies B-Lymphocyte Subsets Case-Control Studies Child Cytokines Diabetes mellitus Type 1 Female Flow Cytometry Gene Expression Regulation Genetic Association Studies Humans Immunophenotyping Male Phenotype Protein Tyrosine Phosphatase Non-Receptor Type 22 Signal Transduction Young Adult
|
|< |
< |
1 |