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Enhancement of immune response against Bordetella spp. by disrupting immunomodulation.
Well-adapted pathogens must evade clearance by the host immune system and the study of how they do this has revealed myriad complex strategies and mechanisms. Classical bordetellae are very closely related subspecies that are...
RORγt+ Treg to Th17 ratios correlate with susceptibility to Giardia infection.
Infections with Giardia are among the most common causes of food and water-borne diarrheal disease worldwide. Here, we investigated Th17, Treg and IgA responses, and alterations in gut microbiota in two mouse lines with varying...
Layered material platform for surface plasmon resonance biosensing.
Plasmonic biosensing has emerged as the most sensitive label-free technique to detect various molecular species in solutions and has already proved crucial in drug discovery, food safety and studies of bio-reactions. This...
Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data.
In many research areas scientists are interested in clustering objects within small datasets while making use of prior knowledge from large reference datasets. We propose a method to apply the machine learning concept of...
The transport of liquids in softwood
Timber is the only widely used construction material we can grow. The wood from which it comes has evolved to provide structural support for the tree and to act as a conduit for fluid flow. These flow paths are crucial for...