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We derive a model of a neuron's interspike interval probability density through analysis of the first passage problem. The fit of our expression to retinal ganglion cell laboratory data extracts three physiologically relevant...

neuron dynamics first passage problem principle of sloppy workmanship Life Sciences

The response of a noninteracting population of identical neurons to a step change in steady synaptic input can be analytically calculated exactly from the dynamical equation that describes the population's evolution in time....

neuron dynamics new equilibrium jump in input exact prediction Life Sciences

The use of a population dynamics approach promises efficient simulation of large assemblages of neurons. Depending on the issues addressed and the degree of realism incorporated in the simulated neurons, a wide range of...

common structure frequency response Stability interacting subpopulations orientation hypercolumn Life Sciences