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Spatial Distribution and Burden of Emerging Arboviruses in French Guiana.
Sarah Bailly, Dominique Rousset, Camille Fritzell, Nathanaël Hozé, Sarrah Ben Achour, Léna Berthelot, Antoine Enfissi, Jessica Vanhomwegen, Henrik Salje, Sandrine Fernandes-Pellerin, Mona Saout, Anne Lavergne, Jean-Claude Manuguerra, Jean-François Carod, Félix Djossou, Simon Cauchemez, Claude Flamand
Sep 10, 2021
Despite the health, social and economic impact of arboviruses in French Guiana, very little is known about the extent to which infection burden is shared between individuals. We conducted a large multiplexed serological survey...
Published by: Viruses
Co-Surveillance of Rotaviruses in Humans and Domestic Animals in Central Uganda Reveals Circulation of Wide Genotype Diversity in the Animals.
Josephine Bwogi, Charles Karamagi, Denis Karuhize Byarugaba, Phionah Tushabe, Sarah Kiguli, Prossy Namuwulya, Samuel S Malamba, Khuzwayo C Jere, Ulrich Desselberger, Miren Iturriza-Gomara
Apr 17, 2023
Rotavirus genotypes are species specific. However, interspecies transmission is reported to result in the emergence of new genotypes. A cross-sectional study of 242 households with 281 cattle, 418 goats, 438 pigs, and 258 humans...
domestic animals genotyping Rotavirus EPIDEMIOLOGY Uganda co-surveillance inter-host species transmission Feces Animals Animals Domestic Cattle Goats Swine Humans Rotavirus Infections Capsid Proteins Antigens Viral Cross-Sectional Studies Phylogeny Genotype
Published by: Viruses
Viroplasms
Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected cells, which are intricately involved in viral replication. Two virus-encoded, non-structural proteins, NSP2 and NSP5, are the main drivers...
Reverse Genetics Rotavirus Replication Cycle Nsp2 liquid-liquid phase separation Viroplasm Protein-Rna Condensates Nsp5 Crispr-Csy4 Genome Editing
Published by: Viruses
Coronavirus Pseudotypes for All Circulating Human Coronaviruses for Quantification of Cross-Neutralizing Antibody Responses.
Alexander Thomas Sampson, Jonathan Heeney, Diego Cantoni, Matteo Ferrari, Maria Suau Sans, Charlotte George, Cecilia Di Genova, Martin Mayora Neto, Sebastian Einhauser, Benedikt Asbach, Ralf Wagner, Helen Baxendale, Nigel Temperton, George Carnell
Sep 28, 2021
The novel coronavirus SARS-CoV-2 is the seventh identified human coronavirus. Understanding the extent of pre-existing immunity induced by seropositivity to endemic seasonal coronaviruses and the impact of cross-reactivity on...
coronavirus neutralization pseudotyped virus covid-19 SARS-CoV-2 Cell Line Animals Humans Coronavirus 229E Human Coronavirus OC43 Human Lentivirus Antibodies Viral Neutralization Tests Transfection Cross Reactions Plasmids Virus Internalization Coronavirus NL63 Human Spike Glycoprotein Coronavirus Middle East Respiratory Syndrome Coronavirus Broadly Neutralizing Antibodies covid-19 SARS-CoV-2
Published by: Viruses
Reproduction Number of the Omicron Variant Triples That of the Delta Variant.
Zhanwei Du, Huaping Hong, ShuQi Wang, Lijia Ma, Caifen Liu, Yuan Bai, Dillon C Adam, Linwei Tian, Lin Wang, Eric H Y Lau, Benjamin J Cowling
May 24, 2022
COVID-19 remains a persistent threat, especially with the predominant Omicron variant emerging in early 2022, presenting with high transmissibility, immune escape, and waning. There is a need to rapidly ramp up global vaccine...
Published by: Viruses
HCMV Antivirals and Strategies to Target the Latent Reservoir.
Human cytomegalovirus (HCMV) is a ubiquitous human herpesvirus. In healthy people, primary infection is generally asymptomatic, and the virus can go on to establish lifelong latency in cells of the myeloid lineage. However, HCMV...
Published by: Viruses
Discovery of Avian Paramyxoviruses APMV-1 and APMV-6 in Shorebirds and Waterfowl in Southern Ukraine.
Amy C Klink, Oleksandr Rula, Mykola Sushko, Maksym Bezymennyi, Oleksandr Mezinov, Oleksandr Gaidash, Xiao Bai, Anton Stegniy, Maryna Sapachova, Roman Datsenko, Sergiy Skorokhod, Vitalii Nedosekov, Nichola J Hill, Levan Ninua, Ganna Kovalenko, Anne Lise Ducluzeau, Andriy Mezhenskyi, Jeremy Buttler, Devin M Drown, Douglas Causey, Borys Stegniy, Anton Gerilovych, Eric Bortz, Denys Muzyka
Apr 17, 2023
Emerging RNA virus infections are a growing concern among domestic poultry industries due to the severe impact they can have on flock health and economic livelihoods. Avian paramyxoviruses (APMV; avulaviruses, AaV) are...
next-generation sequencing wild birds viral ecology APMV MinION Azov-Black Sea region in Ukraine surveillance of avian paramyxoviruses Animals Animals Wild Birds Avulavirus Newcastle disease virus Phylogeny Ukraine
Published by: Viruses