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Results: 3
T lymphocyte senescence is attenuated in Parkinson's disease.
Antonina Kouli, Melanie Jensen, Vanesa Papastavrou, Kirsten M Scott, Claire Kolenda, Craig Parker, Imtiaz H Solim, Marta Camacho, Carmen Martin-Ruiz, Caroline H Williams-Gray
Nov 22, 2021
Background
Immune involvement is well-described in Parkinson's disease (PD), including an adaptive T lymphocyte response. Given the increasing prevalence of Parkinson's disease in older age, age-related dysregulation of...
Published by: Journal of neuroinflammation
Systemic inflammation alters the neuroinflammatory response
Philipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri L H Carpenter, Mathew R Guilfoyle, Peter J A Hutchinson, Adel Helmy, Eric Peter Thelin
Oct 28, 2021
Background
Neuroinflammation following traumatic brain injury (TBI) has been shown to be associated with secondary injury development; however, how systemic inflammatory mediators affect this is not fully understood. The...
Published by: Journal of neuroinflammation
Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y<sub>6</sub> receptor in mice.
Stefan Milde, Francesca W van Tartwijk, Anna Vilalta, Tamara C Hornik, Jacob M Dundee, Mar Puigdellívol, Guy C Brown
Nov 22, 2021
Inflammation may contribute to multiple brain pathologies. One cause of inflammation is lipopolysaccharide/endotoxin (LPS), the levels of which are elevated in blood and/or brain during bacterial infections, gut dysfunction and...
Phagocytosis Cell Death neurodegeneration Microglia Neuroinflammation Parkinson’s disease Phagoptosis P2Y6R
Published by: Journal of neuroinflammation