Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies
Rachel Waller,
Ruth Narramore,
Julie E. Simpson,
Paul R. Heath,
Nikita Verma,
Megan Tinsley,
Jordan R. Barnes,
Hanna T. Haris,
Frances E. Henderson,
Fiona E. Matthews,
Connor D. Richardson,
Carol Brayne,
Paul G. Ince,
Raj N. Kalaria,
Stephen B. Wharton,
CFAS
May 27, 2021
Abstract: White matter lesions (WML) are common in the ageing brain, often arising in a field effect of diffuse white matter abnormality. Although WML are associated with cerebral small vessel disease (SVD) and Alzheimer’s...