ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19.
Maik Pietzner,
Robert Lorenz Chua,
Eleanor Wheeler,
Katharina Jechow,
Julian DS Willett,
Helena Radbruch,
Saskia Trump,
Bettina Heidecker,
Hugo Zeberg,
Frank L Heppner,
Roland Eils,
Marcus A Mall,
J Brent Richards,
Leif-Erik Sander,
Irina Lehmann,
Sören Lukassen,
Nicholas J Wareham,
Christian Conrad,
Claudia Langenberg
Aug 15, 2022
Despite two years of intense global research activity, host genetic factors that predispose to a poorer prognosis of COVID-19 infection remain poorly understood. Here, we prioritise eight robust (e.g., ELF5) or suggestive but...