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Results: 3
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error.
Anthony M Musolf, Annechien EG Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, Consortium for Refractive Error and Myopia (CREAM), Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M van Duijn, Virginie JM Verhoeven, Caroline CW Klaver, Joan E Bailey-Wilson
Jan 04, 2023
Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
Anna S. E. Cuomo, Daniel D. Seaton, Davis J. McCarthy, Iker Martinez, Marc Jan Bonder, Jose Garcia-Bernardo, Shradha Amatya, Pedro Madrigal, Abigail Isaacson, Florian Buettner, Andrew Knights, Kedar Nath Natarajan, Ludovic Vallier, John C. Marioni, Mariya Chhatriwala, Oliver Stegle, Chukwuma A. Agu, Alex Alderton, Petr Danecek, Rachel Denton, Richard Durbin, Daniel J. Gaffney, Angela Goncalves, Reena Halai, Sarah Harper, Christopher M. Kirton, Anja Kolb-Kokocinski, Andreas Leha, Shane A. McCarthy, Yasin Memari, Minal Patel, Ewan Birney, Francesco Paolo Casale, Laura Clarke, Peter W. Harrison, Helena Kilpinen, Ian Streeter, Davide Denovi, Ruta Meleckyte, Natalie Moens, Fiona M. Watt, Willem H. Ouwehand, Angus I. Lamond, Dalila Bensaddek, Philip Beales
Feb 09, 2021
Abstract: Recent developments in stem cell biology have enabled the study of cell fate decisions in early human development that are impossible to study in vivo. However, understanding how development varies across individuals...
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Nicola D. Kerrison, Erin Oerton, Mine Koprulu, Jian’an Luan, Aroon D. Hingorani, Steve A. Williams, Nicholas J. Wareham, Claudia Langenberg
Nov 24, 2021
Abstract: Affinity-based proteomics has enabled scalable quantification of thousands of protein targets in blood enhancing biomarker discovery, understanding of disease mechanisms, and genetic evaluation of drug targets in...