Search
Results: 6
mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity
Marco Pagani, Noemi Barsotti, Alice Bertero, Stavros Trakoshis, Laura Ulysse, Andrea Locarno, Ieva Miseviciute, Alessia De Felice, Carola Canella, Kaustubh Supekar, Alberto Galbusera, Vinod Menon, Raffaella Tonini, Gustavo Deco, Michael V. Lombardo, Massimo Pasqualetti, Alessandro Gozzi
Oct 19, 2021
Abstract: Postmortem studies have revealed increased density of excitatory synapses in the brains of individuals with autism spectrum disorder (ASD), with a putative link to aberrant mTOR-dependent synaptic pruning. ASD is also...
Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits
Jon Palacios-Filardo, Matt Udakis, Giles A. Brown, Benjamin G. Tehan, Miles S. Congreve, Pradeep J. Nathan, Alastair J. H. Brown, Jack R. Mellor
Sep 16, 2021
Abstract: Acetylcholine release in the hippocampus plays a central role in the formation of new memory representations. An influential but largely untested theory proposes that memory formation requires acetylcholine to enhance...
Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits.
Jon Palacios-Filardo, Matt Udakis, Giles A Brown, Benjamin G Tehan, Miles S Congreve, Pradeep J Nathan, Alastair JH Brown, Jack R Mellor
Dec 24, 2021
Acetylcholine release in the hippocampus plays a central role in the formation of new memory representations. An influential but largely untested theory proposes that memory formation requires acetylcholine to enhance responses...
Mouse visual cortex contains a region of enhanced spatial resolution
Enny H. van Beest, Sreedeep Mukherjee, Lisa Kirchberger, Ulf H. Schnabel, Chris van der Togt, Rob R. M. Teeuwen, Areg Barsegyan, Arne F. Meyer, Jasper Poort, Pieter R. Roelfsema, Matthew W. Self
Jun 29, 2021