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Results: 19
Embracing the positive
Abstract: One-in-two people suffering from mental health problems develop such distress before or during adolescence. Research has shown that distress can predict itself well over time. Yet, little is known about how well...
The gap between perceived mental health needs and actual service utilization in Australian adolescents.
Md Irteja Islam, Fakir Md Yunus, Samia Naz Isha, Enamul Kabir, Rasheda Khanam, Alexandra Martiniuk
Mar 31, 2022
Despite being highly prevalent, adolescent mental health problems are undertreated. To better understand the mental health treatment gap, we assessed the prevalence and correlates of help-seeking, including perceived need for...
Embracing the positive
Abstract: One-in-two people suffering from mental health problems develop such distress before or during adolescence. Research has shown that distress can predict itself well over time. Yet, little is known about how well...
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Chris Eijsbouts, Tenghao Zheng, Nicholas A. Kennedy, Ferdinando Bonfiglio, Carl A. Anderson, Loukas Moutsianas, Joanne Holliday, Jingchunzi Shi, Suyash Shringarpure, Alexandru-Ioan Voda, Gianrico Farrugia, Andre Franke, Matthias Hübenthal, Gonçalo Abecasis, Matthew Zawistowski, Anne Heidi Skogholt, Eivind Ness-Jensen, Kristian Hveem, Tõnu Esko, Maris Teder-Laving, Alexandra Zhernakova, Michael Camilleri, Guy Boeckxstaens, Peter J. Whorwell, Robin Spiller, Gil McVean, Mauro D’Amato, Luke Jostins, Miles Parkes, Michelle Agee, Stella Aslibekyan, Adam Auton, Robert K. Bell, Katarzyna Bryc, Sarah K. Clark, Sarah L. Elson, Kipper Fletez-Brant, Pierre Fontanillas, Nicholas A. Furlotte, Pooja M. Gandhi, Karl Heilbron, Barry Hicks, David A. Hinds, Karen E. Huber, Ethan M. Jewett, Yunxuan Jiang, Aaron Kleinman, Keng-Han Lin, Nadia K. Litterman, Marie K. Luff, Jey C. McCreight, Matthew H. McIntyre, Kimberly F. McManus, Joanna L. Mountain, Sahar V. Mozaffari, Priyanka Nandakumar, Elizabeth S. Noblin, Carrie A. M. Northover, Jared O’Connell, Aaron A. Petrakovitz, Steven J. Pitts, G. David Poznik, J. Fah Sathirapongsasuti, Anjali J. Shastri, Janie F. Shelton, Chao Tian, Joyce Y. Tung, Robert J. Tunney, Vladimir Vacic, Xin Wang, Amir S. Zare, Purna Kashyap, Lin Chang, Emeran Mayer, Margaret Heitkemper, Gregory S. Sayuk, Tamar Ringel-Kulka, Yehuda Ringel, William D. Chey, Shanti Eswaran, Juanita L. Merchant, Robert J. Shulman, Luis Bujanda, Koldo Garcia-Etxebarria, Aldona Dlugosz, Greger Lindberg, Peter T. Schmidt, Pontus Karling, Bodil Ohlsson, Susanna Walter, Åshild O. Faresjö, Magnus Simren, Jonas Halfvarson, Piero Portincasa, Giovanni Barbara, Paolo Usai-Satta, Matteo Neri, Gerardo Nardone, Rosario Cuomo, Francesca Galeazzi, Massimo Bellini, Anna Latiano, Lesley Houghton, Daisy Jonkers, Alexander Kurilshikov, Rinse K. Weersma, Mihai Netea, Jonas Tesarz, Annika Gauss, Miriam Goebel-Stengel, Viola Andresen, Thomas Frieling, Christian Pehl, Rainer Schaefert, Beate Niesler, Wolfgang Lieb, Kurt Hanevik, Nina Langeland, Knut-Arne Wensaas, Sverre Litleskare, Maiken E. Gabrielsen, Laurent Thomas, Vincent Thijs, Robin Lemmens, Lukas Van Oudenhove, Mira Wouters
Nov 06, 2021
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
Abstract Multiple psychiatric disorders have been associated with abnormalities in both the innate and adaptive immune systems. The role of these abnormalities in pathogenesis, and whether they...
Mary-Ellen Lynall, Blagoje Soskic, James Hayhurst, Jeremy Schwartzentruber, Daniel F Levey, Gita A Pathak, Renato Polimanti, Joel Gelernter, Murray B Stein, Gosia Trynka, Menna R Clatworthy, Ed Bullmore
Oct 15, 2022
The psychiatric phenotypes of 1q21 distal deletion and duplication
Stefanie C. Linden, Cameron J. Watson, Jacqueline Smith, Samuel J. R. A. Chawner, Thomas M. Lancaster, Ffion Evans, Nigel Williams, David Skuse, F. Lucy Raymond, Jeremy Hall, Michael J. Owen, David E. J. Linden, LeeAnne Green-Snyder, Wendy K. Chung, Anne M. Maillard, Sébastien Jacquemont, Marianne B. M. van den Bree
Feb 04, 2021
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Chris Eijsbouts, Tenghao Zheng, Nicholas A. Kennedy, Ferdinando Bonfiglio, Carl A. Anderson, Loukas Moutsianas, Joanne Holliday, Jingchunzi Shi, Suyash Shringarpure, Alexandru-Ioan Voda, Gianrico Farrugia, Andre Franke, Matthias Hübenthal, Gonçalo Abecasis, Matthew Zawistowski, Anne Heidi Skogholt, Eivind Ness-Jensen, Kristian Hveem, Tõnu Esko, Maris Teder-Laving, Alexandra Zhernakova, Michael Camilleri, Guy Boeckxstaens, Peter J. Whorwell, Robin Spiller, Gil McVean, Mauro D’Amato, Luke Jostins, Miles Parkes, Michelle Agee, Stella Aslibekyan, Adam Auton, Robert K. Bell, Katarzyna Bryc, Sarah K. Clark, Sarah L. Elson, Kipper Fletez-Brant, Pierre Fontanillas, Nicholas A. Furlotte, Pooja M. Gandhi, Karl Heilbron, Barry Hicks, David A. Hinds, Karen E. Huber, Ethan M. Jewett, Yunxuan Jiang, Aaron Kleinman, Keng-Han Lin, Nadia K. Litterman, Marie K. Luff, Jey C. McCreight, Matthew H. McIntyre, Kimberly F. McManus, Joanna L. Mountain, Sahar V. Mozaffari, Priyanka Nandakumar, Elizabeth S. Noblin, Carrie A. M. Northover, Jared O’Connell, Aaron A. Petrakovitz, Steven J. Pitts, G. David Poznik, J. Fah Sathirapongsasuti, Anjali J. Shastri, Janie F. Shelton, Chao Tian, Joyce Y. Tung, Robert J. Tunney, Vladimir Vacic, Xin Wang, Amir S. Zare, Purna Kashyap, Lin Chang, Emeran Mayer, Margaret Heitkemper, Gregory S. Sayuk, Tamar Ringel-Kulka, Yehuda Ringel, William D. Chey, Shanti Eswaran, Juanita L. Merchant, Robert J. Shulman, Luis Bujanda, Koldo Garcia-Etxebarria, Aldona Dlugosz, Greger Lindberg, Peter T. Schmidt, Pontus Karling, Bodil Ohlsson, Susanna Walter, Åshild O. Faresjö, Magnus Simren, Jonas Halfvarson, Piero Portincasa, Giovanni Barbara, Paolo Usai-Satta, Matteo Neri, Gerardo Nardone, Rosario Cuomo, Francesca Galeazzi, Massimo Bellini, Anna Latiano, Lesley Houghton, Daisy Jonkers, Alexander Kurilshikov, Rinse K. Weersma, Mihai Netea, Jonas Tesarz, Annika Gauss, Miriam Goebel-Stengel, Viola Andresen, Thomas Frieling, Christian Pehl, Rainer Schaefert, Beate Niesler, Wolfgang Lieb, Kurt Hanevik, Nina Langeland, Knut-Arne Wensaas, Sverre Litleskare, Maiken E. Gabrielsen, Laurent Thomas, Vincent Thijs, Robin Lemmens, Lukas Van Oudenhove, Mira Wouters
Nov 22, 2021
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD)
Hemmings Wu, Marwan Hariz, Veerle Visser-Vandewalle, Ludvic Zrinzo, Volker A. Coenen, Sameer A. Sheth, Chris Bervoets, Matilda Naesström, Patric Blomstedt, Terry Coyne, Clement Hamani, Konstantin Slavin, Joachim K. Krauss, Kai G. Kahl, Takaomi Taira, Chencheng Zhang, Bomin Sun, Hiroki Toda, Thomas Schlaepfer, Jin Woo Chang, Jean Régis, Rick Schuurman, Michael Schulder, Paresh Doshi, Philip Mosley, Anujan Poologaindran, Gabriel Lázaro-Muñoz, Joshua Pepper, Gaston Schechtmann, Anders Fytagoridis, Daniel Huys, Antonio Gonçalves-Ferreira, Pierre-François D’Haese, Joseph Neimat, Giovanni Broggi, Osvaldo Vilela-Filho, Jürgen Voges, Ahmed Alkhani, Takeshi Nakajima, Raphaelle Richieri, Diana Djurfeldt, Philippe Fontaine, Roberto Martinez-Alvarez, Yasushi Okamura, Jennifer Chandler, Katsushige Watanabe, Juan A. Barcia, Blanca Reneses, Andres Lozano, Loes Gabriëls, Antonio De Salles, Casey H. Halpern, Keith Matthews, Joseph J. Fins, Bart Nuttin
Jan 19, 2021
Abstract: A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (OCD) can be considered an established therapy. In 2014, the World Society for Stereotactic and...
The psychiatric phenotypes of 1q21 distal deletion and duplication
Stefanie C. Linden, Cameron J. Watson, Jacqueline Smith, Samuel J. R. A. Chawner, Thomas M. Lancaster, Ffion Evans, Nigel Williams, David Skuse, F. Lucy Raymond, Jeremy Hall, Michael J. Owen, David E. J. Linden, LeeAnne Green-Snyder, Wendy K. Chung, Anne M. Maillard, Sébastien Jacquemont, Marianne B. M. van den Bree
Mar 04, 2021
MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints.
Andrea Vergallo, Simone Lista, Yuhai Zhao, Pablo Lemercier, Stefan J Teipel, Marie-Claude Potier, Marie-Odile Habert, Bruno Dubois, Walter J Lukiw, Harald Hampel, INSIGHT-preAD study group, Alzheimer Precision Medicine Initiative (APMI)
Jan 27, 2021
There is substantial experimental evidence for dysregulation of several microRNA (miRNA) expression levels in Alzheimer's disease (AD). MiRNAs modulate critical brain intracellular signaling pathways and are associated with AD...
Dorsal and ventral striatal dopamine D1 and D2 receptors differentially modulate distinct phases of serial visual reversal learning
Global population attributable fraction of potentially modifiable risk factors for mental disorders
Elena Dragioti, Joaquim Radua, Marco Solmi, Celso Arango, Dominic Oliver, Samuele Cortese, Peter B. Jones, Jae Il Shin, Christoph U. Correll, Paolo Fusar-Poli
Apr 07, 2023
Numerous risk factors for mental disorders have been identified. However, we do not know how many disorders we could prevent and to what extent by modifying these risk factors. This study quantifies the Population Attributable...
Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders.
MD Hettwer, S Larivière, BY Park, OA van den Heuvel, L Schmaal, OA Andreassen, CRK Ching, M Hoogman, J Buitelaar, D van Rooij, DJ Veltman, DJ Stein, B Franke, TGM van Erp, ENIGMA ADHD Working Group, ENIGMA Autism Working Group, ENIGMA Bipolar Disorder Working Group, ENIGMA Major Depression Working Group, ENIGMA OCD Working Group, ENIGMA Schizophrenia Working Group, N Jahanshad, PM Thompson, SI Thomopoulos, RAI Bethlehem, BC Bernhardt, SB Eickhoff, SL Valk
Nov 15, 2022
Larger left hippocampal presubiculum is associated with lower risk of antisocial behavior in healthy adults with childhood conduct history
Abstract Conduct Disorder (CD) is defined as aggressive, antisocial, and rule-breaking behavior during childhood. It is a major risk factor for developing antisocial personality disorder (ASPD) in...
AmirHussein Abdolalizadeh, Kamyar Moradi, Mohammad Amin Dabbagh Ohadi, Fatemeh Sadat Mirfazeli, Reza Rajimehr
Apr 15, 2023
Embracing the positive
Abstract: One-in-two people suffering from mental health problems develop such distress before or during adolescence. Research has shown that distress can predict itself well over time. Yet, little is known about how well...
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
Ellen Verhoef, Jakob Grove, Chin Yang Shapland, Ditte Demontis, Stephen Burgess, Dheeraj Rai, Anders D. Børglum, Beate St Pourcain
Nov 12, 2021
Abstract: Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are complex co-occurring neurodevelopmental conditions. Their genetic architectures reveal striking similarities but also differences...