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Ordered progression of mitosis requires precise control in abundance of mitotic regulators. The anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase plays a key role by directing ubiquitin-mediated destruction of...

(APC/C) Aurora A KEN degron ubiquitin acceptor Ubiquitination Amino Acid Motifs Anaphase-Promoting Complex-Cyclosome Aurora Kinase A Cell Line Humans Mitosis Protein Binding Substrate Specificity Ubiquitination