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Results: 10
Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation.
HHV-8 KSHV NK cell receptor ligands herpesvirus host cell restriction factors lytic reactivation Proteomics Viral immune evasion Antigens Differentiation T-Lymphocyte Cell Line DNA-Directed DNA Polymerase Down-Regulation Endothelial Cells Gene Library Gene Ontology Genes Viral Genetic Testing Herpesvirus 8 Human Humans immunomodulation Kinetics Ligands Mutation Proteome Proteomics Sarcoma Kaposi Up-Regulation Viral Proteins Virus Activation eIF-2 Kinase
NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
Motaz M Fadul, Claire J Garwood, Rachel Waller, Navonna Garrett, Paul R Heath, Fiona E Matthews, Carol Brayne, Stephen B Wharton, Julie E Simpson
Jan 10, 2020
N-myc downstream regulated gene 2 (NDRG2) Ageing brain astrocyte Neurofibrillary Tangles Aged Aged 80 and over aging Alzheimer Disease Antigens CD Antigens Differentiation Myelomonocytic Astrocytes Brain DNA Damage Excitatory Amino Acid Transporter 2 Gene Expression Regulation Glial Fibrillary Acidic Protein Glutamate-Ammonia Ligase Humans Microglia Neurofibrillary Tangles Tumor Suppressor Proteins tau Proteins
CD3- leukocytes present in the human uterus during early placentation
The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells.
Nicholas Bredenkamp, Giuliano Giuseppe Stirparo, Jennifer Nichols, Austin Smith, Ge Guo
Apr 05, 2019
Interleukin-15 and interferon-gamma participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production.
Isidoro González-Alvaro, Carmen Domínguez-Jiménez, Ana M Ortiz, Vanessa Núñez-González, Pedro Roda-Navarro, Elena Fernández-Ruiz, David Sancho, Francisco Sánchez-Madrid
Jun 14, 2011
A proteomic time course through the differentiation of human induced pluripotent stem cells into hepatocyte-like cells.
Tracey Hurrell, Charis-Patricia Segeritz, Ludovic Vallier, Kathryn S Lilley, Allan D Cromarty
Mar 11, 2019
Numerous in vitro models endeavour to mimic the characteristics of primary human hepatocytes for applications in regenerative medicine and pharmaceutical science. Mature hepatocyte-like cells (HLCs) derived from human induced...
Microglial immunophenotype in dementia with Alzheimer's pathology.
Thais Minett, John Classey, Fiona E Matthews, Marie Fahrenhold, Mariko Taga, Carol Brayne, Paul G Ince, James AR Nicoll, Delphine Boche, MRC CFAS
Aug 14, 2017
BACKGROUND: Genetic risk factors for Alzheimer's disease imply that inflammation plays a causal role in development of the disease. Experimental studies suggest that microglia, as the brain macrophages, have diverse functions...
Alzheimer’s disease Apolipoprotein E Dementia Microglia neuropathology Aged Aged 80 and over Alzheimer Disease Antigens CD Antigens Differentiation Myelomonocytic Calcium-Binding Proteins Cohort Studies Cytokines DNA-Binding Proteins Dementia Diagnosis Female HLA-DR Antigens Humans Male Mental Status Schedule Methionine Sulfoxide Reductases Microfilament Proteins Microglia Neuropsychological Tests Receptors IgG
Highly porous scaffolds of PEDOT
Anne Géraldine Guex, Jennifer L Puetzer, Astrid Armgarth, Elena Littmann, Eleni Stavrinidou, Emmanuel P Giannelis, George G Malliaras, Molly M Stevens
Mar 27, 2018
UNLABELLED: Conjugated polymers have been increasingly considered for the design of conductive materials in the field of regenerative medicine. However, optimal scaffold properties addressing the complexity of the desired tissue...
Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation.
Pedro Madrigal, Siwei Deng, Yuliang Feng, Stefania Militi, Kim Jee Goh, Reshma Nibhani, Rodrigo Grandy, Anna Osnato, Daniel Ortmann, Stephanie Brown, Siim Pauklin
Feb 25, 2023
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.
PJ Brown, KK Wong, SL Felce, L Lyne, H Spearman, EJ Soilleux, LM Pedersen, MB Møller, TM Green, DM Gascoyne, AH Banham
Dec 17, 2018
The FOXP1 (forkhead box P1) transcription factor is a marker of poor prognosis in diffuse large B-cell lymphoma (DLBCL). Here microarray analysis of FOXP1-silenced DLBCL cell lines identified differential regulation of immune...
Adult Aged Aged 80 and over Antibodies Monoclonal Murine-Derived Antigens Differentiation B-Lymphocyte Antineoplastic Combined Chemotherapy Protocols B-Lymphocytes cyclophosphamide Doxorubicin Female Forkhead Transcription Factors Gene Expression Regulation Neoplastic Germinal Center HLA-DR alpha-Chains Histocompatibility Antigens Class II Humans Lymphocyte Activation Lymphoma Large B-Cell Diffuse Male Middle Aged Neoplasm Staging Nuclear Proteins prednisone RNA Small Interfering Repressor Proteins Rituximab Signal Transduction Survival Analysis Trans-Activators Vincristine