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Genetic, lifestyle, and health-related characteristics of adults without celiac disease who follow a gluten-free diet
Thomas J Littlejohns, Amanda Y Chong, Naomi E Allen, Matthew Arnold, Kathryn E Bradbury, Alexander J Mentzer, Elizabeth J Soilleux, Jennifer L Carter
May 13, 2021
BACKGROUND: The number of gluten-free diet followers without celiac disease (CD) is increasing. However, little is known about the characteristics of these individuals. OBJECTIVES: We address this issue by investigating a wide...
Classification of intestinal T-cell receptor repertoires using machine learning methods can identify patients with coeliac disease regardless of dietary gluten status.
Andrew D Foers, M Saad Shoukat, Oliver E Welsh, Killian Donovan, Russell Petry, Shelley C Evans, Michael Eb FitzPatrick, Nadine Collins, Paul Klenerman, Anna Fowler, Elizabeth J Soilleux
Dec 03, 2020
In coeliac disease (CeD), immune-mediated small intestinal damage is precipitated by gluten, leading to variable symptoms and complications, occasionally including aggressive T-cell lymphoma. Diagnosis, based primarily on...
Identification of peculiar gene expression profile in peripheral blood mononuclear cells (PBMC) of celiac patients on gluten free diet.
Moris Sangineto, Giusi Graziano, Simona D'Amore, Roberto Salvia, Giuseppe Palasciano, Carlo Sabbà, Michele Vacca, Marica Cariello
Sep 20, 2018
Celiac disease (CD) is a systemic disorder characterized by an immune-mediated reaction to gluten and a wide spectrum of clinical manifestations. Currently, the main treatment of CD is represented by adherence to a gluten-free...