Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations
E Wheeler,
A Leong,
C-T Liu,
M-F Hivert,
RJ Strawbridge,
C Podmore,
M Li,
J Yao,
X Sim,
J Hong,
AY Chu,
W Zhang,
X Wang,
P Chen,
NM Maruthur,
BC Porneala,
SJ Sharp,
Y Jia,
EK Kabagambe,
L-C Chang,
W-M Chen,
CE Elks,
DS Evans,
Q Fan,
F Giulianini,
MJ Go,
J-J Hottenga,
Y Hu,
AU Jackson,
S Kanoni,
YJ Kim,
ME Kleber,
C Ladenvall,
C Lecoeur,
S-H Lim,
Y Lu,
A Mahajan,
C Marzi,
MA Nalls,
P Navarro,
IM Nolte,
LM Rose,
DV Rybin,
S Sanna,
Y Shi,
DO Stram,
F Takeuchi,
SP Tan,
PJ van der Most,
JV Van Vliet-Ostaptchouk,
A Wong,
L Yengo,
W Zhao,
A Goel,
MT Martinez Larrad,
D Radke,
P Salo,
T Tanaka,
EPA van Iperen,
G Abecasis,
S Afaq,
BZ Alizadeh,
AG Bertoni,
A Bonnefond,
Y Böttcher,
EP Bottinger,
H Campbell,
OD Carlson,
C-H Chen,
YS Cho,
WT Garvey,
C Gieger,
MO Goodarzi,
H Grallert,
A Hamsten,
CA Hartman,
C Herder,
CA Hsiung,
J Huang,
M Igase,
M Isono,
T Katsuya,
C-C Khor,
W Kiess,
K Kohara,
P Kovacs,
J Lee,
W-J Lee,
B Lehne,
H Li,
J Liu,
S Lobbens,
J Luan,
V Lyssenko,
T Meitinger,
T Miki,
I Miljkovic,
S Moon,
A Mulas,
G Müller,
M Müller-Nurasyid,
R Nagaraja,
M Nauck,
JS Pankow,
O Polasek,
I Prokopenko,
PS Ramos,
L Rasmussen-Torvik,
W Rathmann,
SS Rich,
NR Robertson,
M Roden,
R Roussel,
I Rudan,
RA Scott,
WR Scott,
B Sennblad,
DS Siscovick,
K Strauch,
L Sun,
M Swertz,
SM Tajuddin,
KD Taylor,
Y-Y Teo,
YC Tham,
A Tönjes,
NJ Wareham,
G Willemsen,
T Wilsgaard,
AD Hingorani,
EPIC-CVD Consortium,
EPIC-InterAct Consortium,
Lifelines Cohort Study,
J Egan,
L Ferrucci,
GK Hovingh,
A Jula,
M Kivimaki,
M Kumari,
I Njølstad,
CNA Palmer,
M Serrano Ríos,
M Stumvoll,
H Watkins,
T Aung,
M Blüher,
M Boehnke,
DI Boomsma,
SR Bornstein,
JC Chambers,
DI Chasman,
Y-DI Chen,
Y-T Chen,
C-Y Cheng,
F Cucca,
EJC de Geus,
P Deloukas,
MK Evans,
M Fornage,
Y Friedlander,
P Froguel,
L Groop,
MD Gross,
TB Harris,
C Hayward,
C-K Heng,
E Ingelsson,
N Kato,
B-J Kim,
W-P Koh,
JS Kooner,
A Körner,
D Kuh,
J Kuusisto,
M Laakso,
X Lin,
Y Liu,
RJF Loos,
PKE Magnusson,
W März,
MI McCarthy,
AJ Oldehinkel,
KK Ong,
NL Pedersen,
MA Pereira,
A Peters,
PM Ridker,
C Sabanayagam,
M Sale,
D Saleheen,
J Saltevo,
PE Schwarz,
WHH Sheu,
H Snieder,
TD Spector,
Y Tabara,
J Tuomilehto,
RM van Dam,
JG Wilson,
JF Wilson,
BHR Wolffenbuttel,
TY Wong,
J-Y Wu,
J-M Yuan,
AB Zonderman,
N Soranzo,
X Guo,
DJ Roberts,
JC Florez,
R Sladek,
J Dupuis,
AP Morris,
E-S Tai,
E Selvin,
JI Rotter,
C Langenberg,
I Barroso,
JB Meigs
Oct 03, 2017
BACKGROUND: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic...