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Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy.
Youguo Niu, Andrew D Kane, Ciara M Lusby, Beth J Allison, Yi Yi Chua, Joepe J Kaandorp, Rhiannon Nevin-Dolan, Thomas J Ashmore, Heather L Blackmore, Jan B Derks, Susan E Ozanne, Dino A Giussani
Sep 05, 2018
allopurinol developmental programming Hypoxia Oxidative Stress Pregnancy Rats allopurinol Animals Enzyme Inhibitors Female Heart Failure Heart Function Tests Hypoxia Male Myocardial Contraction Oxidative Stress Pregnancy Pregnancy Complications Rats Receptor Muscarinic M2 Receptors Adrenergic beta Sarcoplasmic Reticulum Calcium-Transporting ATPases sympathetic nervous system xanthine oxidase