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Results: 14
Active surveillance of prostate cancer
BACKGROUND: Active surveillance is considered a mainstream strategy in the management of patients with low-risk prostate cancer. A mission-critical step in implementing a robust active surveillance program and plan its resource...
Subchondral bone in osteoarthritis
Histomorphometry Magnetic Resonance Imaging Osteoarthritis Subchondral bone texture analysis Aged Aged 80 and over Analysis of Variance Arthroplasty Replacement Knee Biopsy Needle Cartilage Articular Cross-Sectional Studies Female Humans Immunohistochemistry Magnetic Resonance Imaging Male Menisci Tibial Middle Aged Observer Variation Osteoarthritis Knee Prognosis Risk Assessment Severity of Illness Index Treatment Outcome United Kingdom
Identification of pathologically insignificant prostate cancer is not accurate in unscreened men.
GL Shaw, BC Thomas, SN Dawson, G Srivastava, SL Vowler, VJ Gnanapragasam, NC Shah, AY Warren, DE Neal
Jun 11, 2018
BACKGROUND: Identification of men harbouring insignificant prostate cancer (PC) is important in selecting patients for active surveillance. Tools have been developed in PSA-screened populations to identify such men based on...
Adenocarcinoma Aged Area Under Curve Biopsy Needle Early Detection of Cancer False Negative Reactions Humans Lymphatic Metastasis Magnetic Resonance Imaging Male Middle Aged Neoplasm Grading Neoplasm Staging Organ Size Patient Selection Predictive Value of Tests Prostate Prostate-specific antigen Prostatic Neoplasms ROC Curve Retrospective Studies Risk Assessment Seminal vesicles Sensitivity and Specificity Tumor Burden Watchful Waiting
Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies.
Leander Van Neste, Alan W Partin, Grant Stewart, Jonathan I Epstein, David J Harrison, Wim Van Criekinge
Apr 13, 2016
DNA Methylation epigenetics high-grade logistic regression prostate neoplasms repeat biopsy significant cancer Adenomatous Polyposis Coli Aged Biopsy Needle DNA Methylation Epigenesis Genetic False Negative Reactions Glutathione S-Transferase pi Humans Male Middle Aged Neoplasm Grading Prostate Prostate-specific antigen Prostatic Neoplasms Risk Factors Tumor Suppressor Proteins
National implementation of multi-parametric magnetic resonance imaging for prostate cancer detection - recommendations from a UK consensus meeting.
Mrishta Brizmohun Appayya, Jim Adshead, Hashim U Ahmed, Clare Allen, Alan Bainbridge, Tristan Barrett, Francesco Giganti, John Graham, Phil Haslam, Edward W Johnston, Christof Kastner, Alexander PS Kirkham, Alexandra Lipton, Alan McNeill, Larissa Moniz, Caroline M Moore, Ghulam Nabi, Anwar R Padhani, Chris Parker, Amit Patel, Jacqueline Pursey, Jonathan Richenberg, John Staffurth, Jan van der Meulen, Darren Walls, Shonit Punwani
Sep 20, 2018
OBJECTIVES: To identify areas of agreement and disagreement in the implementation of multi-parametric magnetic resonance imaging (mpMRI) of the prostate in the diagnostic pathway. MATERIALS AND METHODS: Fifteen UK experts in...
consensus methods multi-parametric MRI prostate cancer Recommendations Biopsy Needle Contrast Media Early Detection of Cancer Education Medical Humans Magnetic Resonance Imaging Male Middle Aged Prostate Prostate-specific antigen Prostatic Neoplasms Quality of Health Care Radiologists Referral and Consultation Research Design Tumor Burden
Does preoperative axillary staging lead to overtreatment of women with screen-detected breast cancer?
AIM: To determine the impact of preoperative axillary ultrasound staging in a screen-detected breast cancer population. MATERIALS AND METHODS: Ultrasound and needle biopsy staging results alongside reference standard sentinel...
Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease.
Zoe Hall, Nicholas J Bond, Tom Ashmore, Francis Sanders, Zsuzsanna Ament, Xinzhu Wang, Andrew J Murray, Elena Bellafante, Sam Virtue, Antonio Vidal-Puig, Michael Allison, Susan E Davies, Albert Koulman, Michele Vacca, Julian L Griffin
Feb 08, 2017
Animals Biopsy Needle Diet High-Fat Diet Western Disease Models Animal Eicosanoids Fatty Liver Humans Immunohistochemistry Liver Cirrhosis Liver Neoplasms Liver Regeneration Male Mass Spectrometry Mice Mice Inbred C57BL non-alcoholic fatty liver disease Phospholipids Prognosis Random Allocation Risk Assessment Severity of Illness Index Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization
Risk factors for the development of invasive cancer in unresected ductal carcinoma in situ.
Anthony J Maxwell, Karen Clements, Bridget Hilton, David J Dodwell, Andrew Evans, Olive Kearins, Sarah E Pinder, Jeremy Thomas, Matthew G Wallis, Alastair M Thompson, Sloane Project Steering Group
Feb 18, 2019
BACKGROUND: The natural history of ductal carcinoma in situ (DCIS) remains uncertain. The risk factors for the development of invasive cancer in unresected DCIS are unclear. METHODS: Women diagnosed with DCIS on needle biopsy...
Breast Cancer DCIS Endocrine therapy invasion Microcalcification SURGERY Adult Age Factors Aged Aged 80 and over Biopsy Needle Breast Carcinoma In Situ Breast Neoplasms Calcinosis Carcinoma Intraductal Noninfiltrating Disease Progression Female Humans Middle Aged Neoplasm Grading Neoplasm Invasiveness Prognosis Registries Risk Factors
A rare case of Rosai-Dorfman disease presenting with cardiac tamponade.
Jason M Tarkin, Virginia Wolstenholme, Michael Sheaff, Mark Westwood, Charlotte Manisty
Feb 01, 2019
A 40-year old man presented to hospital with exertional dyspnoea.
The influence of prostate-specific antigen density on positive and negative predictive values of multiparametric magnetic resonance imaging to detect Gleason score 7-10 prostate cancer in a repeat biopsy setting.
Nienke L Hansen, Tristan Barrett, Brendan Koo, Andrew Doble, Vincent Gnanapragasam, Anne Warren, Christof Kastner, Ola Bratt
May 21, 2018
image fusion Magnetic Resonance Imaging prostate biopsy prostate cancer prostate-specific antigen density transperineal biopsy Aged Biopsy Needle Humans Image-guided biopsy Magnetic Resonance Imaging Male Middle Aged Neoplasm Grading Predictive Value of Tests Prostate Prostate-specific antigen Prostatic Neoplasms Retrospective Studies
Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative.
Farzana Pashankar, Juliet P Hale, Ha Dang, Mark Krailo, William E Brady, Carlos Rodriguez-Galindo, James C Nicholson, Matthew J Murray, Deborah F Bilmire, Sara Stoneham, G Suren Arul, Thomas A Olson, Daniel Stark, Furqan Shaikh, James F Amatruda, Allan Covens, David M Gershenson, A Lindsay Frazier
Sep 23, 2016
Adult Chemotherapy ovarian immature teratoma Pediatric Adolescent Adult Age Factors Analysis of Variance Biopsy Needle Chemotherapy Adjuvant Child Cohort Studies Disease-Free Survival Female Humans Immunohistochemistry Middle Aged Neoplasm Invasiveness Neoplasm Recurrence Local Neoplasm Staging Ovarian Neoplasms Registries Risk Assessment Survival Analysis Teratoma Young Adult
Multi-transcript profiling in archival diagnostic prostate cancer needle biopsies to evaluate biomarkers in non-surgically treated men.
BACKGROUND: Most biomarkers in prostate cancer have only been evaluated in surgical cohorts. The value of these biomarkers in a different therapy context remains unclear. Our objective was to test a panel of surgical biomarkers...
Aged Androgen Antagonists Antineoplastic Agents Hormonal Biomarkers Biopsy Needle Gene Expression Profiling Humans Immunohistochemistry Male Middle Aged Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prostatic Neoplasms Proton Therapy Recurrence Reproducibility of Results Retrospective Studies Treatment Outcome
Multiparametric Prostate Magnetic Resonance Imaging and Cognitively Targeted Transperineal Biopsy in Patients With Previous Abdominoperineal Resection and Suspicion of Prostate Cancer.
Nienke L Hansen, Iztok Caglic, Laurence H Berman, Christof Kastner, Andrew Doble, Tristan Barrett
May 10, 2016
Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies.
Leander Van Neste, Alan W Partin, Grant D Stewart, Jonathan I Epstein, David J Harrison, Wim Van Criekinge
Aug 14, 2017
DNA Methylation epigenetics high-grade logistic regression prostate neoplasms repeat biopsy significant cancer Adenomatous Polyposis Coli Aged Biopsy Needle DNA Methylation Epigenesis Genetic False Negative Reactions Glutathione S-Transferase pi Humans Male Middle Aged Neoplasm Grading Prostate Prostate-specific antigen Prostatic Neoplasms Risk Factors Tumor Suppressor Proteins