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Results: 5
Development of Novel Riboswitches for Synthetic Biology in the Green Alga Chlamydomonas.
Payam Mehrshahi, Ginnie Trinh DT Nguyen, Aleix Gorchs Rovira, Andrew Sayer, Marcel Llavero-Pasquina, Michelle Lim Huei Sin, Elliot J Medcalf, Gonzalo I Mendoza-Ochoa, Mark A Scaife, Alison G Smith
Jun 01, 2020
Reaction-Diffusion Patterning of DNA-Based Artificial Cells.
Adrian Leathers, Michal Walczak, Ryan A Brady, Assala Al Samad, Jurij Kotar, Michael J Booth, Pietro Cicuta, Lorenzo Di Michele
Sep 29, 2022
Biological cells display complex internal architectures with distinct micro environments that establish the chemical heterogeneity needed to sustain cellular functions. The continued efforts to create advanced cell mimics...
DNA Nanostructures for Targeted Antimicrobial Delivery.
Ioanna Mela, Pedro P Vallejo-Ramirez, Stanislaw Makarchuk, Graham Christie, David Bailey, Robert M Henderson, Hiroshi Sugiyama, Masayuki Endo, Clemens F Kaminski
Apr 17, 2020
We report the use of DNA origami nanostructures, functionalized with aptamers, as a vehicle for delivering the antibacterial enzyme lysozyme in a specific and efficient manner. We test the system against Gram-positive (Bacillus...
DNA nanostructures antimicrobial Atomic force microscopy bionanotechnology dSTORM Animals Anti-Bacterial Agents Aptamers Nucleotide Bacillus subtilis COS Cells Chlorocebus aethiops DNA Drug Carriers Enzymes Immobilized Escherichia coli Microbial Sensitivity Tests Muramidase NANOSTRUCTURES Nucleic Acid Conformation
Aptamer-modified gold nanoparticles for rapid aggregation-based detection of inflammation
Susan Giorgi-Coll, María J Marín, Olajumoke Sule, Peter J Hutchinson, Keri LH Carpenter
Dec 04, 2019
Characterization of RNA aptamers that disrupt the RUNX1-CBFbeta/DNA complex.
Jenny L Barton, David HJ Bunka, Stuart E Knowling, Pascal Lefevre, Alan J Warren, Constanze Bonifer, Peter G Stockley
Jan 29, 2020
The transcription factor RUNX1 (AML1) is an important regulator of haematopoiesis, and an important fusion partner in leukaemic translocations. High-affinity DNA binding by RUNX1 requires the interaction of the RUNX1...