Search

Results: 21
Picocavities
Jeremy J Baumberg
Aug 06, 2022
Picocavities are sub-nanometer-scale optical cavities recently found to trap light, which are formed by single-atom defects on metallic facets. Here, we develop simple picocavity models and discuss what is known and unknown...
Published by:
One-step fabrication of hollow-channel gold nanoflowers with excellent catalytic performance and large single-particle SERS activity.
Hollow metallic nanostructures have shown potential in various applications including catalysis, drug delivery and phototherapy, owing to their large surface areas, reduced net density, and unique optical properties. In this...
Published by:
Measurement of the Raman spectra and hygroscopicity of four pharmaceutical aerosols as they travel from pressurised metered dose inhalers (pMDI) to a model lung.
Particle inhalation is an effective and rapid delivery method for a variety of pharmaceuticals, particularly bronchodilation drugs used for treating asthma and COPD. Conditions of relative humidity and temperature inside the...
Published by:
Raman micro-spectroscopy for accurate identification of primary human bronchial epithelial cells.
Live cell Raman micro-spectroscopy is emerging as a promising bioanalytical technique for label-free discrimination of a range of different cell types (e.g. cancer cells and fibroblasts) and behaviors (e.g. apoptosis). The aim...
Published by:
Intracellular SERS nanoprobes for distinction of different neuronal cell types.
Distinction between closely related and morphologically similar cells is difficult by conventional methods especially without labeling. Using nuclear-targeted gold nanoparticles (AuNPs) as intracellular probes we demonstrate the...
Published by:
1064 nm Dispersive Raman Microspectroscopy and Optical Trapping of Pharmaceutical Aerosols.
Raman spectroscopy is a powerful tool for investigating chemical composition. Coupling Raman spectroscopy with optical microscopy (Raman microspectroscopy) and optical trapping (Raman tweezers) allows microscopic length scales...
Published by:
DNA origami based assembly of gold nanoparticle dimers for surface-enhanced Raman scattering.
Plasmonic sensors are extremely promising candidates for label-free single-molecule analysis but require exquisite control over the physical arrangement of metallic nanostructures. Here we employ self-assembly based on the DNA...
Published by:
Label-free monitoring of tissue biochemistry following traumatic brain injury using Raman spectroscopy.
Traumatic brain injury (TBI) constitutes a major cause of death and long-term disability. At present, we lack methods to non-invasively track tissue biochemistry and hence select appropriate interventions for patients. We...
Published by: