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Plaque Structural Stress Estimations Improve Prediction of Future Major Adverse Cardiovascular Events After Intracoronary Imaging.
Adam J Brown, Zhongzhao Teng, Patrick A Calvert, Nikil K Rajani, Orla Hennessy, Nitesh Nerlekar, Daniel R Obaid, Charis Costopoulos, Yuan Huang, Stephen P Hoole, Martin Goddard, Nick EJ West, Jonathan H Gillard, Martin R Bennett
Jun 09, 2016
Atherosclerosis Autopsy Coronary Disease Myocardial Infarction Prospective Studies Acute Coronary Syndrome Aged Angina Stable Coronary Artery Disease Coronary Vessels Disease-Free Survival Female Fibrosis Humans Kaplan-Meier Estimate Male Middle Aged Necrosis Percutaneous Coronary Intervention Plaque Atherosclerotic Predictive Value of Tests Proportional Hazards Models Prospective Studies Risk Factors Rupture Spontaneous Severity of Illness Index Stress Mechanical Time Factors Treatment Outcome Ultrasonography Interventional Vascular Calcification
Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention.
George R Abraham, Duuamene Nyimanu, Rhoda E Kuc, Janet J Maguire, Anthony P Davenport, Stephen P Hoole
Nov 19, 2022
OBJECTIVE: Coronary microvascular dysfunction (CMD) can complicate successful percutaneous coronary intervention (PCI). The potent endogenous vasoconstrictor peptide Endothelin-1 (ET-1) may be an important mediator. To...
Neutrophil-derived microparticles are released into the coronary circulation following percutaneous coronary intervention in acute coronary syndrome patients.
Gonzalo J Martínez, Jennifer Y Barraclough, Shirley Nakhla, Vivian Kienzle, Stacy Robertson, Ziad Mallat, David S Celermajer, Sanjay Patel
Jun 21, 2018
To evaluate (i) local coronary and systemic levels of microparticles (MP) in acute coronary syndrome (ACS) and stable angina pectoris (SAP) patients and (ii) their release after plaque disruption with percutaneous coronary...
Acute Coronary Syndromes Microparticles Neutrophils Acute Coronary Syndrome Aged Angina Stable Angioplasty Balloon Coronary Antigens CD Cell Adhesion Molecules Cell-Derived Microparticles Coronary Artery Disease Coronary Circulation Female GPI-Linked Proteins Humans Interleukin-6 Male Middle Aged Neutrophils P-Selectin Peroxidase Plaque Atherosclerotic
Urine proteomics in the diagnosis of stable angina.
Ulf Neisius, Thomas Koeck, Harald Mischak, Sabrina H Rossi, Erin Olson, David M Carty, Jane A Dymott, Anna F Dominiczak, Colin Berry, Keith G Oldroyd, Christian Delles
Jul 27, 2018
BACKGROUND: We have previously described a panel of 238 urinary polypeptides specific for established severe coronary artery disease (CAD). Here we studied this polypeptide panel in patients with a wider range of CAD severity....
Controversies in Diagnostic Imaging of Patients With Suspected Stable and Acute Chest Pain Syndromes.
Leslee J Shaw, Ron Blankstein, David L Brown, Sanket S Dhruva, Pamela S Douglas, Tessa SS Genders, Raymond J Gibbons, John P Greenwood, Raymond Kwong, Jonathon Leipsic, John J Mahmarian, David Maron, Eike Nagel, Ed Nicol, Koen Nieman, Patricia A Pellikka, Rita F Redberg, Jonathan Weir-McCall, Michelle C Williams, Y Chandrasekhar
Jan 10, 2020
There has been a tremendous growth quantity of high-quality imaging evidence in the area of acute and stable ischemic heart disease (SIHD). A number of recent comparative effectiveness trials have spurned significant...
Anatomy Chest Pain functional testing Imaging Acute Coronary Syndrome Adult Aged Aged 80 and over Angina Stable Cardiac Imaging Techniques Coronary Artery Disease Diagnosis Differential Female Humans Male Middle Aged Observer Variation Patient Selection Predictive Value of Tests Prognosis Reproducibility of Results Risk Factors