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Results: 1
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p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response.
Hiroyoshi Hattori
,
Rekin's Janky
,
Wilfried Nietfeld
,
Stein Aerts
,
M Madan Babu
,
Ashok R Venkitaraman
Feb 13, 2020
The human DNA damage response (DDR) triggers profound changes in gene expression, whose nature and regulation remain uncertain. Although certain micro-(mi)RNA species including miR34, miR-18, miR-16 and miR-143 have been...
AP-1
activator protein-1
DDR
DNA damage response
DNA damage response
E2F1
transcription factor E2F1
FOXM1
forkhead box protein M1
NF-k B
nuclear factor-k B
NGS
next-generation sequencing
TF
transcription factor
TP53
tumour protein p53
clinical outcome
computational analysis
double stranded DNA breaks
DSBs
ionizing radiation
IR
miRNA
micro-RNA
micro-RNA
misc RNA
miscellaneous RNA
next-generation sequencing
p53
scRNA
small cytoplasmic RNA
snRNA
small nuclear RNA
snoRNA
small nucleolar RNA
tRNA
transfer RNA
Cell Line
DNA Damage
DNA Repair
Gene Expression Regulation
Gene Expression Regulation
Neoplastic
Genome
Genome
Human
Humans
MicroRNAs
Neoplasms
Organ Specificity
Tumor Suppressor Protein p53
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