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Results: 2
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Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors.
Eugen Brailoiu
,
Sumita Chakraborty
,
G Cristina Brailoiu
,
Pingwei Zhao
,
Jeffrey L Barr
,
Marc A Ilies
,
Ellen M Unterwald
,
Mary E Abood
,
Colin W Taylor
Jan 28, 2019
Sigma-1 receptors (Sig-1Rs) are integral ER membrane proteins. They bind diverse ligands, including psychoactive drugs, and regulate many signaling proteins, including the inositol 1,4,5-trisphosphate receptors (IP3Rs) that...
Ca(2+)
G-protein-coupled receptor
IP(3) receptor
Sigma-1 receptor
Bradykinin
Choline
intracellular messenger
neurotransmitter
phospholipase C
Phospholipase D
Animals
Calcium Signaling
Cell Line
Choline
Humans
Inositol 1
4
5-Trisphosphate Receptors
MCF-7 Cells
Mice
Phospholipase D
Receptors
sigma
Published by:
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Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1.
Shyam Srivats
,
Dilshan Balasuriya
,
Mathias Pasche
,
Gerard Vistal
,
J Michael Edwardson
,
Colin W Taylor
,
Ruth D Murrell-Lagnado
Feb 29, 2016
Calcium
Calcium Channels
Calcium Signaling
Cell Line
Cell Line
Tumor
Cell Membrane
Endoplasmic Reticulum
HEK293 Cells
HeLa Cells
Humans
Membrane Proteins
Neoplasm Proteins
ORAI1 Protein
Receptors
sigma
Stromal Interaction Molecule 1
Published by: