A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification.
B Edginton-White,
A Maytum,
SG Kellaway,
DK Goode,
P Keane,
I Pagnuco,
SA Assi,
L Ames,
M Clarke,
PN Cockerill,
B Göttgens,
JB Cazier,
C Bonifer
Jan 19, 2023
Developmental control of gene expression critically depends on distal cis-regulatory elements including enhancers which interact with promoters to activate gene expression. To date no global experiments have been conducted that...