The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure
Robert E. Turnbull,
Louise Fairall,
Almutasem Saleh,
Emma Kelsall,
Kyle L. Morris,
T. J. Ragan,
Christos G. Savva,
Aditya Chandru,
Christopher J. Millard,
Olga V. Makarova,
Corinne J. Smith,
Alan M. Roseman,
Andrew M. Fry,
Shaun M. Cowley,
John W. R. Schwabe
Jun 26, 2021
Abstract: MiDAC is one of seven distinct, large multi-protein complexes that recruit class I histone deacetylases to the genome to regulate gene expression. Despite implications of involvement in cell cycle regulation and in...