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Characterisation of proguanylin expressing cells in the intestine – evidence for constitutive luminal secretion
Florent Serge Dye, Pierre Larraufie, Richard Kay, Tamana Darwish, Juraj Rievaj, Deborah A. Goldspink, Claire L. Meek, Stephen J. Middleton, Richard H. Hardwick, Geoffrey P. Roberts, Jennifer L. Percival-Alwyn, Tris Vaughan, Franco Ferraro, Benjamin G. Challis, Stephen O’Rahilly, Maria Groves, Fiona M. Gribble, Frank Reimann
Oct 29, 2020
Abstract: Guanylin, a peptide implicated in regulation of intestinal fluid secretion, is expressed in the mucosa, but the exact cellular origin remains controversial. In a new transgenic mouse model fluorescent reporter protein...