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Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome
Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Natasja Van den Vreken, Andre G. Skirtach, Sanjay Sinha, Julie De Backer, Jolanda van Hengel
Oct 07, 2021
Abstract: Marfan syndrome (MFS) is a systemic disorder of connective tissue caused by pathogenic variants in the fibrillin-1 (FBN1) gene. Myocardial dysfunction has been demonstrated in MFS patients and mouse models, but little...
Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome
Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Natasja Van den Vreken, Andre G. Skirtach, Sanjay Sinha, Julie De Backer, Jolanda van Hengel
Oct 07, 2020
Abstract: Marfan syndrome (MFS) is a systemic disorder of connective tissue caused by pathogenic variants in the fibrillin-1 (FBN1) gene. Myocardial dysfunction has been demonstrated in MFS patients and mouse models, but little...
The feasibility of the PAM intervention to support treatment-adherence in people with hypertension in primary care
Aikaterini Kassavou, Venus Mirzaei, Sonia Shpendi, James Brimicombe, Jagmohan Chauhan, Debi Bhattacharya, Felix Naughton, Wendy Hardeman, Helen Eborall, Miranda Van Emmenis, Anna De Simoni, Amrit Takhar, Pankaj Gupta, Prashanth Patel, Cecilia Mascolo, Andrew Toby Prevost, Stephen Morris, Simon Griffin, Richard J. McManus, Jonathan Mant, Stephen Sutton
Apr 26, 2021
Abstract: The PAM intervention is a behavioural intervention to support adherence to anti-hypertensive medications and therefore to lower blood pressure. This feasibility trial recruited 101 nonadherent patients (54% male, mean...