Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Gwen Tolhurst,
Helen Heffron,
Yu Shan Lam,
Helen E Parker,
Abdella M Habib,
Eleftheria Diakogiannaki,
Jennifer Cameron,
Johannes Grosse,
Frank Reimann,
Fiona M Gribble
Nov 08, 2017
Interest in how the gut microbiome can influence the metabolic state of the host has recently heightened. One postulated link is bacterial fermentation of "indigestible" prebiotics to short-chain fatty acids (SCFAs), which in...