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Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient.
Alejandro Jiménez-Sánchez, Danish Memon, Stephane Pourpe, Harini Veeraraghavan, Yanyun Li, Hebert Alberto Vargas, Michael B Gill, Kay J Park, Oliver Zivanovic, Jason Konner, Jacob Ricca, Dmitriy Zamarin, Tyler Walther, Carol Aghajanian, Jedd D Wolchok, Evis Sala, Taha Merghoub, Alexandra Snyder, Martin L Miller
Jul 24, 2017
Safety and utility of image-guided research biopsies in relapsed high-grade serous ovarian carcinoma-experience of the BriTROC consortium.
T Goranova, D Ennis, AM Piskorz, G Macintyre, LA Lewsley, J Stobo, C Wilson, D Kay, RM Glasspool, M Lockley, E Brockbank, A Montes, A Walther, S Sundar, R Edmondson, GD Hall, A Clamp, C Gourley, M Hall, C Fotopoulou, H Gabra, S Freeman, L Moore, M Jimenez-Linan, J Paul, JD Brenton, IA McNeish
Nov 13, 2018
BACKGROUND: Investigating tumour evolution and acquired chemotherapy resistance requires analysis of sequential tumour material. We describe the feasibility of obtaining research biopsies in women with relapsed ovarian...
Adult Aged Aged 80 and over Carcinoma Class I Phosphatidylinositol 3-Kinases DNA Mutational Analysis DNA Neoplasm ErbB Receptors Feasibility Studies Female Humans Image-guided biopsy Liver Liver Neoplasms Lymph Nodes Lymphatic Metastasis Middle Aged Neoplasm Grading Omentum Ovarian Neoplasms PTEN Phosphohydrolase Pain Peritoneal Neoplasms Peritoneum Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins B-raf Proto-Oncogene Proteins p21(ras) Tumor Suppressor Protein p53