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Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression.
Suman De, Daniel R Whiten, Francesco S Ruggeri, Craig Hughes, Margarida Rodrigues, Dimitrios I Sideris, Christopher G Taylor, Francesco A Aprile, Serge Muyldermans, Tuomas PJ Knowles, Michele Vendruscolo, Clare Bryant, Kaj Blennow, Ingmar Skoog, Silke Kern, Henrik Zetterberg, David Klenerman
Jul 24, 2019
Alzheimer’s disease cerebrospinal fluid Disease mechanism mild cognitive impairment protein aggregation Structure-function relation Super-resolution imaging Aged Alzheimer Disease Amyloid beta-Peptides Animals Biomarkers Camelids New World Cognitive Dysfunction Disease Progression Female Humans Male Protein Aggregates tau Proteins
An 8.22 Mb Assembly and Annotation of the Alpaca (Vicugna pacos) Y Chromosome.
Matthew J Jevit, Brian W Davis, Caitlin Castaneda, Andrew Hillhouse, Rytis Juras, Vladimir A Trifonov, Ahmed Tibary, Jorge C Pereira, Malcolm A Ferguson-Smith, Terje Raudsepp
Apr 12, 2021
The unique evolutionary dynamics and complex structure make the Y chromosome the most diverse and least understood region in the mammalian genome, despite its undisputable role in sex determination, development, and male...