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Results: 1
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miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.
Martin Connolly
,
Benjamin E Garfield
,
Alexi Crosby
,
Nick W Morrell
,
Stephen J Wort
,
Paul R Kemp
Apr 27, 2020
The microRNA miR-1 is an important regulator of muscle phenotype including cardiac muscle. Down-regulation of miR-1 has been shown to occur in left ventricular hypertrophy but its contribution to right ventricular hypertrophy in...
Animals
Cardiomegaly
Gene Expression Regulation
hypertrophy
Right Ventricular
Male
MicroRNAs
pulmonary arterial hypertension
Rats
Rats
Sprague-Dawley
Receptor
Transforming Growth Factor-beta Type I
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