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Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis
Ville Wallenius, Erik Elias, Erik Elebring, Bauke Haisma, Anna Casselbrant, Pierre Larraufie, Emma Spak, Frank Reimann, Carel W le Roux, Neil G Docherty, Fiona M Gribble, Lars Fändriks
Nov 13, 2019
Diabetes mellitus enterocyte biology glucagen-like peptides obesity surgery small bowel 3-Hydroxybutyric Acid Anastomosis Roux-en-Y Animals Caloric Restriction Cells Cultured Dietary Fats Emulsions Enteroendocrine Cells Fat Emulsions Intravenous Female Gastric Bypass Glucagon-Like Peptide 1 Humans Hydroxymethylglutaryl-CoA Synthase Intestinal Mucosa Jejunum ketone bodies Ketones Liver Male Mice Mice Inbred C57BL Middle Aged Phospholipids Postoperative Period Preoperative Period Primary Cell Culture Soybean Oil
β-Hydroxybutyrate Accumulates in the Rat Heart during Low-Flow Ischaemia with Implications for Functional Recovery
Ross Lindsay, Sophie Dieckmann, Dominika Krzyzanska, Dominic Manetta-Jones, James West, Cecilia Castro, Julian Griffin, Andrew Murray
Aug 24, 2021
Heart ischaemia Langendorff Biochemistry cardiomyocyte Cell Biology chemical biology rat 3-Hydroxybutyric Acid Animals Chromatography Liquid Citric Acid Cycle Heart Hydroxymethylglutaryl-CoA Synthase Ischemia ketone bodies Male Mitochondria Myocardial Ischemia Myocytes Cardiac Oxidation-Reduction Rats Rats Wistar Tandem Mass Spectrometry
Sex-Specific Differences in Lysine, 3-Hydroxybutyric Acid and Acetic Acid in Offspring Exposed to Maternal and Postnatal High Linoleic Acid Diet, Independent of Diet.
Nirajan Shrestha, Steven D Melvin, Daniel R McKeating, Olivia J Holland, James SM Cuffe, Anthony V Perkins, Andrew J McAinch, Deanne H Hryciw
Sep 25, 2021
BACKGROUND: Linoleic acid (LA) is an essential polyunsaturated fatty acid (PUFA) that is required for foetal growth and development. Excess intake of LA can be detrimental for metabolic health due to its pro-inflammatory...
Linoleic Acid metabolite Offspring sex 3-Hydroxybutyric Acid Acetic Acid Adult Children Animals Animals Newborn Diet Diet High-Fat Female Lactation Linoleic Acid Lysine Male Maternal Nutritional Physiological Phenomena Plasma Pregnancy prenatal exposure delayed effects principal component analysis ROC Curve Rats Inbred WKY Sex Characteristics