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Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the most common of which is the non-synonymous single...

STRUCTURE HOMOLOGY RECOGNITION PREDICTION AMINO-ACID SUBSTITUTION BINDING SURFACES DATABASE LARGE-SCALE NON-SYNONYMOUS SNPS PROTEIN STABILITY CHANGES SINGLE NUCLEOTIDE POLYMORPHISMS SUPPORT VECTOR MACHINES

STRUCTURE HOMOLOGY RECOGNITION PREDICTION AMINO-ACID SUBSTITUTION BINDING SURFACES DATABASE LARGE-SCALE NON-SYNONYMOUS SNPS PROTEIN STABILITY CHANGES SINGLE NUCLEOTIDE POLYMORPHISMS SUPPORT VECTOR MACHINES