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Anogenital distance endocrine disruption paracetamol testicular descent testicular dysgenesis syndrome toxicology Acetaminophen Anal Canal Biomarkers Body Weights and Measures Female Humans Infant Newborn Male Pregnancy prenatal exposure delayed effects Testis

Paracetamol (acetaminophen) is the preferred antipyretic/analgesic for pregnant women as it is believed there are no adverse fetal effects at the recommended dose. However, emerging evidence suggests that intrauterine...

Acetaminophen Anogenital distance endocrine disruption fetal exposure paracetamol reproductive development toxicology

amorphous Crystallization GLASS Stability Terahertz Spectroscopy Acetaminophen Calorimetry Differential Scanning Crystallization Drug Stability Flufenamic Acid Indomethacin Kinetics Molecular Dynamics Simulation Naproxen Simvastatin Temperature Terahertz Spectroscopy X-Ray Diffraction

BACKGROUND AND AIMS: Premature neonates require regular ophthalmological examination, generally indirect ophthalmoscopy, to screen for retinopathy of prematurity (ROP). Conventional analgesia is provided with topical anesthetic...

analgesic eye examination indirect ophthalmoscopy Neonatal Nitrous Oxide opioids paracetamol retinopathy of prematurity screening tools topical anesthesia Acetaminophen Analgesia Fentanyl Humans Infant Newborn Nitrous Oxide Pain Pain Measurement retinopathy of prematurity

Fast disintegrating tablets have commonly been used for fast oral drug delivery to patients with swallowing difficulties. The different characteristics of the pore structure of such formulations influence the liquid transport...

disintegration Liquid transport MICROSTRUCTURE Pharmaceutical tablets porous media swelling terahertz Acetaminophen Calcium Carbonate Cellulose Chemistry Pharmaceutical Dose-Response Relationship Drug excipients Humans Kinetics Porosity Tablets Terahertz Spectroscopy Theophylline

PURPOSE: Paracetamol has been associated with a reduction in blood pressure, especially in febrile, critically-ill adults. We hypothesised that blood pressure would fall following administration of paracetamol in critically-ill...

Child Critical Care Fever paracetamol Physiologic monitoring Acetaminophen Adolescent Adult Analgesics Non-Narcotic blood pressure Child Child Hospitalized Child Preschool Critical Illness Female Fever Heart Rate Hemodynamics Humans Infant Infant Newborn Prospective Studies Vascular Resistance