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Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube
Andrew C Symonds
,
Clare Buckley
,
Chrlotte A Williams
,
Jonathan DW Clarke
Nov 30, 2020
Using the zebrafish neural tube as a model, we uncover the in vivo mechanisms allowing the generation of two opposing apical epithelial surfaces within the centre of an initially unpolarised, solid organ. We show that Mpp5a and...
Adhesions
Epithelial tube
Morphogenesis
Neural Tube
Zebrafish
Animals
Cell Polarity
Epithelial Cells
Gene Expression Regulation
Developmental
Guanylate Cyclase
Intercellular Junctions
Membrane Proteins
Morphogenesis
Neural Tube
Zebrafish
Zebrafish Proteins
rab GTP-Binding Proteins
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