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Results: 12
Inclusion of multiple high-risk histopathological criteria improves the prediction of adjuvant chemotherapy efficacy in lung adenocarcinoma.
Marco Sereno, Zhangyi He, Claire R Smith, Juvenal Baena, Madhumita Das, Robert K Hastings, Grace Rake, Dean A Fennell, Apostolos Nakas, David A Moore, John Le Quesne
Apr 20, 2021
AIMS: The decision to consider adjuvant chemotherapy (AC) for non-small cell lung cancer is currently governed by clinical stage. This study aims to assess other routinely collected pathological variables related to metastasis...
Adenocarcinoma of Lung Adjuvant Biomarkers Chemotherapy Histology Tumour Adenocarcinoma of Lung Aged Aged 80 and over Antineoplastic Agents Chemotherapy Adjuvant Female Humans Lung Neoplasms Male Middle Aged Neoplasm Invasiveness Neoplasm Staging Prognosis Retrospective Studies Survival Rate Treatment Outcome
Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant
Yi Yang, Catherine Back, Melissa Gräwert, Ayla Wahid, Harriet Denton, Rebecca Kildani, Joshua Paulin, Kristin Wörner, Wolgang Kaiser, Dmitri i. Svergun, Asel Sartbaeva, Andrew Watts, Kevin J Marchbank, Johannes Van Den Elsen
Jan 11, 2019
Co-ligation of the B cell antigen receptor with complement receptor 2 on B-cells via a C3d-opsonised antigen complex significantly lowers the threshold required for B cell activation. Consequently, fusions of antigens with C3d...
Adjuvant complement Immune Evasion Staphycoccus aureus vaccine /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant
Yi Yang, Catherine Back, Melissa Gräwert, Ayla Wahid, Harriet Denton, Rebecca Kildani, Joshua Paulin, Kristin Wörner, Wolgang Kaiser, Dmitri i. Svergun, Asel Sartbaeva, Andrew Watts, Kevin J Marchbank, Johannes Van Den Elsen
Jan 11, 2019
Co-ligation of the B cell antigen receptor with complement receptor 2 on B-cells via a C3d-opsonised antigen complex significantly lowers the threshold required for B cell activation. Consequently, fusions of antigens with C3d...
Adjuvant complement Immune Evasion Staphycoccus aureus vaccine /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
SpeS
C. Coral Dominguez-Medina, Nicola L. Rash, Sylvain Robillard, Carl Robinson, Androulla Efstratiou, Karen Broughton, Julian Parkhill, Matthew T.G. Holden, Maria R. Lopez-Alvarez, Romain Paillot, Andrew S. Waller
Jun 24, 2020
Bacterial superantigens (sAgs) are powerful activators of the immune response that trigger unspecific T cell responses accompanied by the release of proinflammatory cytokines. Streptococcus equi (S. equi) and Streptococcus...
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
If irradiated tumor cells could be rendered immunogenic, they would provide a safe, broad, and patient-specific array of antigens for immunotherapies. Prior approaches have emphasized genetic transduction of live tumor cells to...
Published by: Rockefeller University
The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma
Tobias Klatte, Kevin M. Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony C. P. Riddick, James N. Armitage, Tevita F. ‘Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J. Pantuck, Grant D. Stewart
Oct 02, 2020
Abstract: Background: The current World Health Organization classification recognises 12 major subtypes of renal cell carcinoma (RCC). Although these subtypes differ on molecular and clinical levels, they are generally managed...
SpeS
C Coral Dominguez-Medina, Nicola L Rash, Sylvain Robillard, Carl Robinson, Androulla Efstratiou, Karen Broughton, Julian Parkhill, Matthew TG Holden, Maria R Lopez-Alvarez, Romain Paillot, Andrew S Waller
Aug 03, 2020
Bacterial superantigens (sAgs) are powerful activators of the immune response that trigger unspecific T cell responses accompanied by the release of proinflammatory cytokines. Streptococcus equi (S. equi) and Streptococcus...
Streptococcus equi Streptococcus zooepidemicus Adjuvant horse immune response strangles superantigen vaccine Adjuvants Immunologic Antigen Presentation Bacterial Proteins Exotoxins Histocompatibility Antigens Class II Humans Membrane Proteins Meningitis Phylogeny Receptors Antigen T-Cell Streptococcal Infections Streptococcus equi Superantigens vaccines
Adjuvant Effect of Orally Applied Preparations Containing Non-Digestible Polysaccharides on Influenza Vaccination in Healthy Seniors
Christiane Laue, Yala Stevens, Monique van Erp, Ekaterina Papazova, Edlyn Soeth, Angelika Pannenbeckers, Ellen Stolte, Ruwen Böhm, Sophie Le Gall, Xavier Falourd, Simon Ballance, Svein H Knutsen, Iris Pinheiro, Sam Possemiers, Paul M Ryan, R Paul Ross, Catherine Stanton, Jerry M Wells, Sylvie van der Werf, Jurriaan J Mes, Juergen Schrezenmeir
Oct 25, 2021
Senior individuals can suffer from immunosenescence and novel strategies to bolster the immune response could contribute to healthy ageing. In this double-blind, randomised, controlled pilot trial, we investigated the ability of...
Adjuvant Arabinoxylan Cold Immunity Influenza non-digestible polysaccharide Prebiotics Vaccination β-glucan Adjuvants Immunologic Administration Oral Aged Double-Blind Method Female Healthy Volunteers Hemagglutination Inhibition Tests Humans Immunization Secondary Influenza A virus H1N1 Subtype Influenza A virus Influenza Vaccines Influenza Human Male Middle Aged Pilot Projects Polysaccharides
The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma
Tobias Klatte, Kevin M Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony CP Riddick, James N Armitage, Tevita F 'Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J Pantuck, Grant D Stewart
Oct 09, 2019
BACKGROUND: The current World Health Organization classification recognises 12 major subtypes of renal cell carcinoma (RCC). Although these subtypes differ on molecular and clinical levels, they are generally managed as the same...
Adjuvant Localised Papillary Prognosis Recurrence SURVEILLANCE Adult Aged Carcinoma Renal Cell Clinical Trials as Topic Cohort Studies Female Humans Incidence Kidney Neoplasms Male Middle Aged Models Statistical Neoplasm Recurrence Local Neoplasm Staging Predictive Value of Tests Prognosis Prospective Studies Research Design Risk Factors Treatment Outcome
VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1)
Elizabeth Smyth, Maren Knödler, Anne Giraut, Murielle Mauer, Magnus Nilsson, Nicole Van Grieken, Anna Dorothea Wagner, Markus Moehler, Florian Lordick
Mar 25, 2020
Background: Perioperative chemotherapy plus surgery is one recommended standard treatment for patients with resectable gastric and esophageal cancer. Even with a multimodality treatment more than half of patients will relapse...
VESTIGE: Adjuvant Immunotherapy in Patients With Resected Esophageal, Gastroesophageal Junction and Gastric Cancer Following Preoperative Chemotherapy With High Risk for Recurrence (N+ and/or R1)
Elizabeth Smyth, Maren Knödler, Anne Giraut, Murielle Mauer, Magnus Nilsson, Nicole Van Grieken, Anna Dorothea Wagner, Markus Moehler, Florian Lordick
Feb 13, 2020
Background: Perioperative chemotherapy plus surgery is one recommended standard treatment for patients with resectable gastric and esophageal cancer. Even with a multimodality treatment more than half of patients will relapse...