Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart
Min Park,
Takanori Nishimura,
Carlos D. Baeza-Garza,
Stuart T. Caldwell,
Pamela Boon Li Pun,
Hiran A. Prag,
Tim Young,
Olga Sauchanka,
Angela Logan,
Marleen Forkink,
Anja V. Gruszczyk,
Tracy A. Prime,
Sabine Arndt,
Alba Naudi,
Reinald Pamplona,
Melinda T. Coughlan,
Mitchel Tate,
Rebecca H. Ritchie,
Federico Caicci,
Nina Kaludercic,
Fabio Di Lisa,
Robin A. J. Smith,
Richard C. Hartley,
Michael P. Murphy,
Thomas Krieg
Nov 18, 2020
Abstract: Purpose: HFpEF (heart failure with preserved ejection fraction) is a major consequence of diabetic cardiomyopathy with no effective treatments. Here, we have characterized Akita mice as a preclinical model of HFpEF and...