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Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis.
Janine S Hähnlein, Reza Nadafi, Tineke A de Jong, Johanna F Semmelink, Ester BM Remmerswaal, Mary Safy, Krijn P van Lienden, Mario Maas, Danielle M Gerlag, Paul P Tak, Reina E Mebius, Heidi Wähämaa, Anca I Catrina, Lisa G M van Baarsen
Aug 10, 2020
BACKGROUND: In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies showed that lymph node stromal cells (LNSCs) maintain...