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The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors.
Kimberley A Roper
,
Heiko Lange
,
Anastasios Polyzos
,
Malcolm B Berry
,
Ian R Baxendale
,
Steven V Ley
Jun 17, 2021
Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no...
Appel reaction
Bromination
flow chemistry
solid-supported reagent
triphenylphosphine monolith
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