Search
Results: 3
Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.
Julia Steinberg, Graham RS Ritchie, Theodoros I Roumeliotis, Raveen L Jayasuriya, Matthew J Clark, Roger A Brooks, Abbie LA Binch, Karan M Shah, Rachael Coyle, Mercedes Pardo, Christine L Le Maitre, Yolande FM Ramos, Rob GHH Nelissen, Ingrid Meulenbelt, Andrew W McCaskie, Jyoti S Choudhary, J Mark Wilkinson, Eleftheria Zeggini
Dec 05, 2017
Aquaporin 1 Arthroplasty Replacement Hip Arthroplasty Replacement Knee Case-Control Studies Chondrocytes Chromatography Liquid Collagen Type I Collagen Type I alpha 1 Chain DNA Methylation Disease Progression Epigenesis Genetic Epigenomics Gene Expression Profiling Gene Regulatory Networks Humans Lectins C-Type Male Mass Spectrometry Osteoarthritis Hip Osteoarthritis Knee Proteomics Sequence Analysis RNA
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M Salmon, Mark Southwood, Rajiv D Machado, Jennifer M Martin, Carmen M Treacy, Katherine Yates, Louise C Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala Aldred, Harm J Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J Simon R Gibbs, Barbara Girerd, Arjan C Houweling, Luke Howard, Marc Humbert, David G Kiely, Gabor Kovacs, Robert V MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F Stein, Jay Suntharalingam, Emilia M Swietlik, Mark R Toshner, David A van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J Wort, Willem H Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D Upton, Martin R Wilkins, Richard C Trembath, Nicholas W Morrell
May 21, 2018
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-β pathway, particularly the bone morphogenetic protein type 2 receptor...
Adenosine Triphosphatases Adult Aquaporin 1 Base Sequence Bone Morphogenetic Protein Receptors Type II Case-Control Studies Familial Primary Pulmonary Hypertension Female Gene Expression Regulation Genetic Predisposition to Disease Growth Differentiation Factor 2 Growth Differentiation Factors HEK293 Cells Humans Male Membrane Transport Proteins Models Molecular Mutation Prognosis SOXF Transcription Factors Signal Transduction Transforming Growth Factor beta whole genome sequencing
Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia.
James S Ware, Louise V Wain, Sarath K Channavajjhala, Victoria E Jackson, Elizabeth Edwards, Run Lu, Keith Siew, Wenjing Jia, Nick Shrine, Sue Kinnear, Mahli Jalland, Amanda P Henry, Jenny Clayton, Kevin M O'Shaughnessy, Martin D Tobin, Victor L Schuster, Stuart Cook, Ian P Hall, Mark Glover
Sep 03, 2019
Aged Aged 80 and over Aquaporin 1 Aquaporin 2 Cohort Studies Dinoprostone Female Genome-Wide Association Study Humans Hyponatremia Male Middle Aged Nephrons Organic Anion Transporters Pharmacogenetics Phenotype Polymorphism Single Nucleotide Prostaglandins Sodium Chloride Symporter Inhibitors Thiazides United Kingdom water