Begin your search of the AGOSR Open Access Database

Search

Reset
Results: 3
Cover Image for Development of a multipurpose scaffold for the display of peptide loops View Article
Development of a multipurpose scaffold for the display of peptide loops
M Rossmann, S J Greive, T Moschetti, M Dinan, M Hyvönen
May 31, 2017
Aurora A CK2alpha peptide display Protein–protein interactions thermostable RadA
Published by:
Cover Image for Ubiquitination site preferences in anaphase promoting complex/cyclosome (APC/C) substrates. View Article
Ubiquitination site preferences in anaphase promoting complex/cyclosome (APC/C) substrates.
Mingwei Min, Ugo Mayor, Catherine Lindon
May 03, 2021
Ordered progression of mitosis requires precise control in abundance of mitotic regulators. The anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase plays a key role by directing ubiquitin-mediated destruction of...
(APC/C) Aurora A KEN degron ubiquitin acceptor Ubiquitination Amino Acid Motifs Anaphase-Promoting Complex-Cyclosome Aurora Kinase A Cell Line Humans Mitosis Protein Binding Substrate Specificity Ubiquitination
Published by:
Cover Image for Allosteric Targeting of Aurora A Kinase Using Small Molecules View Article
Allosteric Targeting of Aurora A Kinase Using Small Molecules
Resmi C Panicker, Anthony G Coyne, Rajavel Srinivasan
Aug 17, 2017
BACKGROUND: Aurora A (AurA) kinase is a key mitotic protein implicated in cancer. Several small molecule inhibitors targeting the ATP binding site of this enzyme are in various stages of clinical development. However, these...
AURKA AurA-TPX2 inhibition Aurora A TPX2 allosteric inhibition Kinase inhibitors proteinprotein interaction type IV inhibitors. Allosteric Regulation Allosteric Site Anacardic Acids Aurora Kinase A Cell Cycle Proteins Cell Line Tumor Felodipine Humans Microtubule-Associated Proteins Nuclear Proteins Protein Binding Protein Kinase Inhibitors
Published by: