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Cover Image for Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome

Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome

S Halabi, E Sekine, B Verstak, NJ Gay, MC Moncrieffe

Feb 23, 2017

BCAP BCAP adaptor MAL/TIRAP PI3 kinase PLCγ2 TIR domain Toll-like receptor Toll-like receptor (TLR) Crystal structure pathway crosstalk phosphatidylinositide 3-kinase (PI 3-kinase) Phosphatidylinositol 4 5-bisphosphate phospholipase C

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