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Pulmonary arterial hypertension (PAH) is estimated to affect between 10 and 50 people per million worldwide. The lack of cure and devastating nature of the disease means that treatment is crucial to arrest rapid clinical...

BMP signalling BMPR2 pulmonary hypertension therapeutics Animals Antihypertensive Agents Arterial Pressure Bone Morphogenetic Protein Receptors Type II Humans Molecular Targeted Therapy pulmonary arterial hypertension Pulmonary Artery Signal Transduction Vascular Remodeling

Axon navigation BMP signalling hereditary spastic paraplegia Neuropilin 1 Spastin Zebrafish Animals Axons Bone Morphogenetic Proteins COS Cells CRISPR-Cas Systems Cell Line Cell Movement Chlorocebus aethiops GTP-Binding Proteins Gene Knockout Techniques Humans Membrane Proteins Motor Neurons Neuropilin-1 Protein Isoforms Spastic Paraplegia Hereditary Spastin Zebrafish Zebrafish Proteins