Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease
Alexandra Pokhilko,
Gaia Brezzo,
Lahiru Handunnetthi,
Raphael Heilig,
Rachel Lennon,
Colin Smith,
Stuart M Allan,
Alessandra Granata,
Sanjay Sinha,
Tao Wang,
Hugh S Markus,
Alexandra Naba,
Roman Fischer,
Tom Van Agtmael,
Karen Horsburgh,
M Zameel Cader
Aug 26, 2021
The extracellular matrix (ECM) is a key interface between the cerebrovasculature and adjacent brain tissues. Deregulation of the ECM contributes to a broad range of neurological disorders. However, despite this importance, our...