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Results: 2
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Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule.
Sofía S Villar
,
James Wason
,
Jack Bowden
Jun 13, 2018
The Gittins index provides a well established, computationally attractive, optimal solution to a class of resource allocation problems known collectively as the multi-arm bandit problem. Its development was originally motivated...
Bayesian adaptive designs
Clinical Trials
Gittins index
multi-armed bandit
Sequential allocation
Algorithms
Bayes Theorem
Biometry
Computer Simulation
Humans
Inflammatory Breast Neoplasms
Models
Statistical
Randomized Controlled Trials as Topic
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Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials
GM Wheeler
,
MJ Sweeting
,
AP Mander
May 05, 2017
dose-escalation
Bayesian adaptive designs
Maximum Tolerated Dose
phase I trials
Published by: