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Results: 8
Estimating the risks of prehospital transfusion of D-positive whole blood to trauma patients who are bleeding in England.
BACKGROUND AND OBJECTIVES: D-negative red cells are transfused to D-negative females of childbearing potential (CBP) to prevent haemolytic disease of the foetus and newborn (HDFN). Transfusion of low-titre group O whole blood...
The INTERVAL trial to determine whether intervals between blood donations can be safely and acceptably decreased to optimise blood supply
Carmel Moore, Jennifer Sambrook, Matthew Walker, Zoe Tolkien, Stephen Kaptoge, David Allen, Susan Mehenny, Jonathan Mant, Emanuele Di Angelantonio, Simon G Thompson, Willem Ouwehand, David J Roberts, John Danesh
Sep 18, 2014
External validation of a predictive model of survival after cytoreductive nephrectomy for metastatic renal cell carcinoma.
Lorenzo Marconi, Roderick de Bruijn, Erik Van Werkhoven, Christian Beisland, Kate Fife, Axel Heidenreich, Anil Kapoor, Jose Karam, Caroline Kauffmann, Tobias Klatte, Boerje Ljungberg, Surena Matin, Daniel Sjoberg, Michael Staehler, Grant D Stewart, Simon Tanguay, Robert Uzzo, Sarah Welsh, Lori Wood, Chris Wood, Axel Bex
Sep 08, 2018
INTRODUCTION: Recent trials have emphasized the importance of a precise patient selection for cytoreductive nephrectomy (CN). In 2013, a nomogram was developed for pre- and postoperative prediction of the probability of death...
cytoreductive nephrectomy Metastatic renal cancer Nomogram selection targeted therapy validation Adrenal Gland Neoplasms Aged Antineoplastic Agents Area Under Curve Blood Transfusion Bone Neoplasms Brain Neoplasms Carcinoma Renal Cell Cytoreduction Surgical Procedures Female Humans Intraoperative Care Kaplan-Meier Estimate Kidney Neoplasms L-Lactate Dehydrogenase Liver Neoplasms Lung Neoplasms Male Middle Aged Molecular Targeted Therapy Neoplasm Metastasis Neoplasm Staging Nephrectomy Nomograms Patient Selection Prognosis Reproducibility of Results Serum Albumin Survival Rate
Development and validation of a universal blood donor genotyping platform
Nicholas S Gleadall, Barbera Veldhuisen, Jeremy Gollub, Adam S Butterworth, John Ord, Christopher J Penkett, Tiffany C Timmer, Carolin M Sauer, Nieke van der Bolt, Colin Brown, Kim Brugger, Alexander T Dilthey, Daniel Duarte, Shane Grimsley, Katja van den Hurk, John M Jongerius, Jessie Luken, Karyn Megy, Gail Miflin, Christopher S Nelson, Femmeke J Prinsze, Jennifer Sambrook, Ilenia Simeoni, Michael Sweeting, Nicole Thornton, Sara Trompeter, Salih Tuna, Ram Varma, Matthew R Walker, NIHR BioResource, John Danesh, David J Roberts, Willem H Ouwehand, Kathleen E Stirrups, Augusto Rendon, Connie M Westhoff, Emanuele Di Angelantonio, C Ellen van der Schoot, William J Astle, Nicholas A Watkins, William J Lane
Jun 17, 2020
Variations in hemoglobin measurement and eligibility criteria across blood donation services are associated with differing low-hemoglobin deferral rates
Saurabh Zalpuri, Bas Romeijn, Elias Allara, Mindy Goldman, Hany Kamel, Jed Gorlin, Ralph Vassallo, Yves Grégoire, Naoko Goto, Peter Flanagan, Joanna Speedy, Andreas Buser, Jose Mauro Kutner, Karin Magnussen, Johanna Castrén, Liz Culler, Harry Sussmann, Femmeke J Prinsze, Kevin Belanger, Veerle Compernolle, Pierre Tiberghien, Jose Manuel Cardenas, Manish J Gandhi, Kamille A West, Cheuk-Kwong Lee, Sian James, Deanne Wells, Laurie J Sutor, Silvano Wendel, Matthew Coleman, Axel Seltsam, Kimberly Roden, Whitney R Steele, Milos Bohonek, Ramir Alcantara, Emanuele Di Angelantonio, Katja van den Hurk, BEST Collaborative Study Group
Jan 10, 2020
BACKGROUND: Determination of blood donor hemoglobin (Hb) levels is a pre-requisite to ensure donor safety and blood product quality. We aimed to identify Hb measurement practices across blood donation services and to what extent...
Modelling the outcomes of different red blood cell transfusion strategies for the treatment of traumatic haemorrhage in the prehospital setting in the United Kingdom.
Barnaby Roberts, Laura Green, Venus Ahmed, Tom Latham, Peter O'Boyle, Mark H Yazer, Rebecca Cardigan
Sep 14, 2022
BACKGROUND AND OBJECTIVES: The limited supply and increasing demand of group O RhD-negative red blood cells (RBCs) have resulted in other transfusion strategies being explored by blood services that carry potential risks but may...
Reappraising the concept of massive transfusion in trauma.
Simon J Stanworth, Timothy P Morris, Christine Gaarder, J Carel Goslings, Marc Maegele, Mitchell J Cohen, Thomas C König, Ross A Davenport, Jean-Francois Pittet, Pär I Johansson, Shubha Allard, Tony Johnson, Karim Brohi
Jun 17, 2011
Massive blood loss protocol 'Code Red' at Papworth Hospital
AIM: To investigate if the massive blood loss protocol 'Code Red' at a specialist cardiothoracic hospital was activated according to local and national guidelines by a closed loop audit. METHODS: Electronic and paper patient...