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Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimer's disease risk in the general population
Jie Zheng, Min Xu, Venexia Walker, Jinqiu Yuan, Roxanna Korologou-Linden, Jamie Robinson, Peiyuan Huang, Stephen Burgess, Shiu Lun Au Yeung, Shan Luo, Michael V Holmes, George Davey Smith, Guang Ning, Weiqing Wang, Tom R Gaunt, Yufang Bi
Sep 15, 2022
AIMS/HYPOTHESIS: Metformin use has been associated with reduced incidence of dementia in diabetic individuals in observational studies. However, the causality between the two in the general population is unclear. This study uses...