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Cover Image for Complotype affects the extent of down-regulation by Factor I of the C3b feedback cycle in vitro.

Complotype affects the extent of down-regulation by Factor I of the C3b feedback cycle in vitro.

E Lay, S Nutland, JE Smith, I Hiles, RAG Smith, DJ Seilly, A Buchberger, W Schwaeble, PJ Lachmann

Oct 09, 2014

C3b feedback cycle Factor I complotype Alleles Complement C3b Complement Factor H Complement Pathway Alternative Feedback Physiological Fibrinogen Gene Expression Regulation Genotype Heterozygote Homozygote Humans Peptide Fragments Polymorphism Single Nucleotide Zymosan

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